Results 101 to 110 of about 2,994,969 (345)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Firms, Nonprofits, and Cooperatives: A Theory of Organizational Choice [PDF]
This paper formalizes the difference between firms, nonprofits, and cooperatives and identifies optimal organizational choice. In a model of quality provision, we find a clear ranking of quality produced: Firms provide lowest and nonprofits highest ...
Herbst, P., Prüfer, J.
core +1 more source
Change Pressure on Organizational Commitment and Identification: Knowledge and Decision-making Competencies in Government Units [PDF]
, 2017 . Staffs in government units may encounter problems of pressure when facing dramatic organizational changes. In an interesting context of administrative merge of Kaohsiung city and county, we examined the influences of change pressure on post-merger ...
HUANG, Wenyi +2 more
core +2 more sources
The Interplay between Intuition and Rationality in Strategic Decision Making: A Paradox Perspective
, 2017 Both intuition and rationality can play important roles in strategic decision making. However, a framework that specifically accounts for the interplay between intuition and rationality is still missing.
G. Calabretta, G. Gemser, N. Wijnberg
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Qualidade da informação e intuição na tomada de decisão organizacional
Perspectivas em Ciência da InformaçãoDiscute a relação entre tomada de decisão no ambiente organizacional e qualidade da informação, considerando a intuição dos decisores. Por meio de questionários distribuídos pessoalmente, foram pesquisados 100 profissionais para saber os atributos da ...
Sueli Angélica do Amaral +1 more
doaj +1 more source
Joint Determination of Internal Organizational Design: Decision-Making, Task Allocation, and Incentive Scheme, [PDF]
This paper studies the issue of designing an optimal organizational form: design for sub-units' task allocation, decision-making structure, and incentive schemes for organizational members.
Keunkwan Ryu, Son Ku Kim
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Frontiers in CognitionDecision fatigue leads to reduced efficiency in the rate and quality of decisions. Thus, examining the reasons behind decision fatigue and comprehending its influence on decision-making in various professional domains is pivotal to improving the decision-
Nurul Ahad Choudhury, Pratima Saravanan
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source