Results 71 to 80 of about 155,401 (311)

Stakeholder value judgments in decision-making on the incorporation, financing, and allocation of new health technologies in limited-resource settings: a potential Brazilian approach

Revista Panamericana de Salud Pública, 2018
Objective. To analyze the value judgments behind cost–benefit tradeoffs made by health stakeholders in deciding whether or not to incorporate new health technologies and how they should be financed and allocated in limited-resource settings in Brazil ...
Luiz Santoro Neto, Fernanda Lessa, Elene Paltrinieri Nardi, Marcos Bosi Ferraz   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

How can continuing professional development better promote shared decision-making? : perspectives from an international collaboration [PDF]

, 2011
Background: Shared decision-making is not widely implemented in healthcare. We aimed to set a research agenda about promoting shared decision-making through continuing professional development.
Neely, C, Politi, MC, Ferdjaoui-Moumjid, Nora, Drolet, R., Schuerman, Janet S, Charo Rodriguez, Borduas, Francine, Griffiths Frances, Politi, M C, Mary C Politi, Cornuz, J., Cheater, Francine M., Desroches Sophie, Cheater Francine M, Tanja Krones, Sullivan Mark D, Martin Härter, Jacques, André, Politi, Mary, Janet S Schuerman, Ferdjaoui-Moumjid Nora, Jacques André, Neely, C., Coutu, Marie-France, Cornuz Jacques, Hilary Bekker, Bekker Hilary, Sophie Desroches, Sullivan, M D, Nora Ferdjaoui-Moumjid, Marie-France Coutu, Ferdjaoui-Moumjid, N, Schuerman, Janet S., Borduas Francine, Joan Sargeant, Härter, M., Krones, Tanja, Härter, M, Légaré France, Cheater, F M, Schuerman, JS, Rodriguez Charo, Schuerman Janet S, Drolet, R, Bekker, H, Neely Claire, Griffiths, Frances, Härter Martin, Politi, Mary C, André Jacques, Jacques Cornuz, Jacques, A, Drolet Renée, Coutu, MF, Rodriguez, C., Cornuz, Jacques, Krones, T, Desroches, Sophie, Coutu, M F, Légaré, F., Stacey, Dawn, Sargeant, J, Schuerman, J.S., Borduas, F., Sargeant, J., Cornuz, J, Labrecque, M., Sullivan, M.D., Politi, Mary C., Politi Mary C, Borduas, F, Rodríguez, C, Sargeant, Joan, Claire Neely, Bekker, H., Coutu, M.F., Stacey, D, Härter, Martin, Cheater, Francine M, Sullivan, Mark D., Sullivan, Mark D, Sullivan, MD, Politi, M.C., Krones, T; https://orcid.org/, Rodriguez, Charo, Griffiths, F., Légaré, France, Sargeant Joan, Cheater, FM, Neely, Claire, Desroches, S, Ferdjaoui-Moumjid, N., Griffiths, F, Schuerman, J S, France Légaré, Dawn Stacey, Drolet, Renée, Cheater, F.M., Krones Tanja, Francine Borduas, Frances Griffiths, Francine M Cheater, Labrecque, Michel, Labrecque Michel, Desroches, S., Michel Labrecque, Krones, T., Labrecque, M, Stacey, D., Coutu Marie-France, Renée Drolet, Jacques, A., Bekker, Hilary, Mark D Sullivan, Légaré, F, Stacey Dawn   +115 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Analysis and Intuition in Strategic Decision Making the Case of California [PDF]

, 2006
This paper reports the results of a study that attempts to assess the effects of decision making circumstances focusing mainly on the approaches applied and the managerial skills and capabilities the decision makers built on during concrete strategic ...
Zoltayné Paprika, Zita
core   +1 more source

JOB SATISFACTION MANAGEMENT AND ITS IMPACT ON BURNOUT AND TURNOVER AMONG AUDITORS

Agora International Journal of Economical Sciences
The paper examines managerial viewpoints related to job satisfaction, burnout, and turnover in auditing companies. Based on in-depth analysis using managerial viewpoints obtained through human resources managers’ or audit managers’ participation in face-
Revaz Lazariashvili, Natia Surmanidze
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Inter-organizational Negotiation and Intra-organizational Power in Shared Decision-making: Early agreements under codecision and their impact on the European Parliament and the Council of Ministers. IHS Political Science Series: 2004, No. 95 [PDF]

, 2004
In this article we argue that closer attention should be paid to the inter-organizational rules of decision-making and their implications for intra-organizational processes.
Farrell, Henry, Héritier, Adrienne.
core  

The Impact of Organizational Citizenship Behavior, Employee Engagement, and Managerial Decision-Making on the Microfinance Institutions Performance

Media Ekonomi dan Manajemen
This study examines the impact of employee organizational citizenship behavior (OCB) and engagement on the performance of microfinance institutions, with a focus on the moderating role of managerial decision-making.
Donni Junipriansa, Ganjar Mohamad Disastra   +1 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source