Results 181 to 190 of about 7,090,393 (298)

Shared decision making and chronic diseases

Allergy, Asthma & Clinical Immunology, 2010
Desroches Sophie
doaj   +1 more source

Heterogeneity in decision-making engagement among total knee arthroplasty patients in China: a cross-sectional study. [PDF]

BMJ Open
Qian H, Chen Y, Yu Z, Yang D, Wang F, Yang C, Qian Y, Lu Q, Cai T, Yuan C.   +9 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Human factors and airway management: focus on the Swiss Airway Guidelines. [PDF]

Front Med (Lausanne)
Balmer C, Casso G, Schoettker P, Savoldelli GL.   +3 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Dual attitudes toward doctors: the role of shared decision-making and empathy in frustrated medical treatment in a randomized trial. [PDF]

Front Public Health
Ying L, Chen Y, Wang X, Huang J, Yan J, Song J, Zhou Q.   +6 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Development of a core outcome set for the evaluation of shared decision-making interventions in healthcare: a study protocol. [PDF]

BMJ Open
Hoffmann C, Butterworth JE, Naye F, Smith M, Nyamapfene T, Lawday S, Avery K, Bekker H, Bravo P, Décary S, Edwards A, Elwyn G, Engelhardt EG, Franco JVA, Garvelink MM, Giguere AM, Härter M, Hoffmann T, Kienlin S, McCaffery K, Noordman J, Olling K, Perestelo-Pérez L, Pieterse AH, Scheibler F, Sepucha K, Ubbink D, Valentine KD, Volk RJ, Wehking F, Yoo SH, Bulbeck H, Cole AC, de Wit M, Finderup J, Geary K, Gunn CM, Hou WH, Housten AJ, Kim MJ, Norma M, Pacheco-Brousseau L, Snede L, Tian C, Toupin-April K, McNair AG.   +45 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source