Results 131 to 140 of about 2,454,117 (316)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
International Journal for Equity in HealthObjectives To explore the perceptions that Colombians have about voluntary private health insurance plans (VPHI) in the health system to identify the tensions that exist between the public and private systems.
Daniel Felipe Patiño-Lugo +8 more
doaj +1 more source
A review of clinical decision-making: Models and current research
, 2007 Aims and objectives: The aim of this paper was to review the current literature with respect to clinical decision-making models and the educational application of models to clinical practice.
Banning, M, Maggi Banning
core +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Humanities & Social Sciences CommunicationsDuring China’s critical period of industrial structural transformation, the relationship between digital finance, industrial structure upgrading, and energy efficiency has become a crucial issue that urgently requires exploration in the process of ...
Haicheng Zhu +4 more
doaj +1 more source
Dynamic utilisation of knowledge in decision making [PDF]
The contribution of this research is a set of novel insights on the interplay of knowledge assets during decision making. Knowledge is conceptualised as a dynamic resource.
Soskic, Nevena
core
Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Medical Decision Making: Analyzing Options in the Face of Uncertainty
, 1983 Papers presented at the fourth annual meeting of the Society for Medical Decision Making are discussed in the context of a review of the rapidly evolving interdisciplinary field of medical decision making (MDM).
Ziporyn, Terra
core +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Cultural Factors in Complex Decision Making
, 2002 Complex decision-making is conceptualised as the process of problem solving in meaningful and important, but complex, dynamic and partially opaque situations.
Stefan Strohschneider +1 more
core +1 more source