Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Decision rules diverge between sympatric Featherfin cichlids despite shared preferences, ecology, and evolutionary history. [PDF]
Tomasek M +5 more
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Optimizing Sequential Decision Rules for Prostate Cancer Biopsy Management: A Multi-Objective Statistical Framework. [PDF]
Qiu J +5 more
europepmc +1 more source
On Robustness of Individualized Decision Rules. [PDF]
Qi Z, Pang JS, Liu Y.
europepmc +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
A Narrative Review of Syncope Decision Rules: A Case for Point-of-Care Cardiac Ultrasound for Cardiac Syncope. [PDF]
Situ-LaCasse E +4 more
europepmc +1 more source
Clinical decision rules in the pre-hospital triage of patients with chest pain. [PDF]
Aarts GWA, Damman P.
europepmc +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Aligning Noninferiority Assumptions and Decision Rules in a Protocol for a Study on Adjunctive Acupuncture for Late-Life Depression. [PDF]
Shiraishi K.
europepmc +1 more source

