Results 101 to 110 of about 4,134,598 (285)
MetrologyThe work of the laboratories does not end with the measurement or examination results. However, there are significant differences between medical laboratories and testing laboratories in how they handle results.
Marco Pradella
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Subjective beliefs formation and elicitation rules : experimental evidence [PDF]
Since they have been increasingly used in economics, elicitation rules for subjective beliefs are under scrutiny. In this paper, we propose an experimental design to compare the performance of such rules.
Jean-Christophe Vergnaud +2 more
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Learning Near-optimal Decision Rules for Energy Efficient Building Control [PDF]
Recent studies suggest that advanced optimization based control methods such as model predictive control (MPC) can increase energy efficiency of buildings.
Jones, Colin +3 more
core +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Cambodian peasant's contribution to rural development: a perspective from Kampong Thom Province [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2010 The paper aims to identify the rationality of peasant communities and their contribution to rural development in Kampong Thom province. To do so, an interdisciplinary analytical framework addresses the dynamics of land use and land tenure, the strategies
Diepart, JC.
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Microarray-Based Cancer Prediction Using Soft Computing Approach
Cancer Informatics, 2009 One of the difficulties in using gene expression profiles to predict cancer is how to effectively select a few informative genes to construct accurate prediction models from thousands or ten thousands of genes.
Xiaosheng Wang, Osamu Gotoh
doaj