Results 121 to 130 of about 308,520 (290)
Awareness and use of five imaging decision rules for musculoskeletal injuries: a systematic review. [PDF]
Int J Emerg Med, 2023 Kharel P +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Simple versus optimal rules as guides to policy [PDF]
This paper contributes to the policy evaluation literature by developing new strategies to study alternative policy rules. We compare optimal rules to simple rules within canonical monetary policy models.
Steven N. Durlauf +3 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Exploring the Health Literacy Behavior Patterns of Male Patients Using an Interpretable Method
Risk Management and Healthcare PolicyLizhen Huang,1,* Yanjun Jin,2,* Ching-Wen Chien,3 Qinyi Xu,3 Yen-Ching Chuang,4– 6 Tao-Hsin Tung6,7 1School of Economics and Management, Fuzhou University, Fuzhou, Fujian, 350108, People’s Republic of China; 2Department of Urology, Taizhou ...
Huang L +5 more
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cost-Sensitive Decision Tree with Multiple Resource Constraints [PDF]
Resource constraints are commonly found in classification tasks. For example, there could be a budget limit on implementation and a deadline for finishing the classification task.
Chia-Chi WU, Kwei TANG, Yen-Liang CHEN
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Microarray-Based Cancer Prediction Using Soft Computing Approach
Cancer Informatics, 2009 One of the difficulties in using gene expression profiles to predict cancer is how to effectively select a few informative genes to construct accurate prediction models from thousands or ten thousands of genes.
Xiaosheng Wang, Osamu Gotoh
doaj
Evidence suggesting that reindeer mothers allonurse according to the direct reciprocity and generalized reciprocity decision rules. [PDF]
PLoS One, 2023 Engelhardt SC +4 more
europepmc +1 more source