Results 121 to 130 of about 259,972 (207)

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

"A cross-sectional analysis of four common clinical decision rules for pulmonary embolism": The need for integrated and evolving approaches. [PDF]

J Cardiovasc Thorac Res
Banisefid E, Javanshir E.
europepmc   +1 more source

Inferring the decision rules that drive co-foraging affiliations in wild mixed-species parrot groups. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Ferdinand V, Pattenden E, Brightsmith DJ, Hobson EA.   +3 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Optimal visual search with highly heuristic decision rules. [PDF]

J Vis
Zhang A, Geisler WS.
europepmc   +1 more source

Targeted Search for Individualized Clinical Decision Rules to Optimize Clinical Outcomes. [PDF]

Stat Biosci, 2022
Wang Y, Zhao Y, Zheng Y.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

From sole crops to strip cropping: Decision rules of frontrunner farmers in The Netherlands. [PDF]

PLoS One
Juventia SD, van Apeldoorn DF, Faber H, Rossing WAH.   +3 more
europepmc   +1 more source

A deep neural network framework to derive interpretable decision rules for accurate traumatic brain injury identification of infants. [PDF]

BMC Med Inform Decis Mak, 2023
Zou B, Mi X, Stone E, Zou F.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source