Results 131 to 140 of about 259,972 (207)

Clinical decision rules for diagnosis of Streptococcus pyogenes sore throat in Fiji: a prospective diagnostic accuracy study. [PDF]

Lancet Reg Health West Pac
Hart JD, Kailawadoko J, Williams T, Mani J, Malo I, Cua T, Caltabiano N, Voss J, Azzopardi K, Parnaby MG, Autar S, Chand K, Lagilagi L, Paka J, Rafai E, Kado J, Frost H, Steer AC.   +17 more
europepmc   +1 more source

A Single Index Model for Longitudinal Outcomes to Optimize Individual Treatment Decision Rules. [PDF]

Stat, 2022
Yao L, Tarpey T.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

To the Editor: Reply to "Clinical Decision Rules: A Starting Place in Medical Education, Not a Destination". [PDF]

J Grad Med Educ
Baggett N.
europepmc   +1 more source

Deciphering human decision rules in motion discrimination. [PDF]

Atten Percept Psychophys, 2021
Huang J, Yu A, Zhou Y, Liu Z.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A New Paradigm for Generative Adversarial Networks based on Randomized Decision Rules. [PDF]

Stat Sin
Kim S, Song Q, Liang F.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Decision Rules in Frequentist and Bayesian Hypothesis Testing: P-Value and Bayes Factor. [PDF]

Int J Public Health
Fordellone M, Schiattarella P, Nicolao G, Signoriello S, Chiodini P.   +4 more
europepmc   +1 more source

Correction to: "Optimal Individualized Decision Rules Using Instrumental Variable Methods". [PDF]

J Am Stat Assoc, 2021
Qiu H, Carone M, Sadikova E, Petukhova M, Kessler RC, Luedtke A.   +5 more
europepmc   +1 more source