Results 151 to 160 of about 308,520 (290)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Authors' Reply: Aligning Noninferiority Assumptions and Decision Rules in a Protocol for a Study on Adjunctive Acupuncture for Late-Life Depression. [PDF]

JMIR Res Protoc
Fu Q, Xiao K, Zhang J, Li Y, Wang Y, Jiang M, Man Z, Yang J, Lu W.   +8 more
europepmc   +1 more source

Methodological approaches based on business rules [PDF]

Business rules and business processes are essential artifacts in defining the requirements of a software system. Business processes capture business behavior, while rules connect processes and thus control processes and business behavior.
Adina UTA, Anca Ioana ANDREESCU
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Differential Diagnosis of Parotid Tumors on Ultrasound: Interobserver Variability and Examiner-Specific Decision Rules-A Machine Learning Approach. [PDF]

Diagnostics (Basel)
Pillong L, Ohnesorg I, Brust LA, Palm J, Schulze-Berge J, Bozzato V, Voges M, Müller A, Garner M, Bozzato A.   +9 more
europepmc   +1 more source

Evaluation of the "hemoptysis" item in clinical decision rules for the diagnosis of pulmonary embolism in the emergency department. [PDF]

Acad Emerg Med, 2022
Bannelier H, Gorlicki J, Penaloza A, Douillet D, Roy PM, Freund Y, Roussel M.   +6 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Personalizing ecological momentary intervention for substance use disorders through data-driven decision rules. [PDF]

Front Psychiatry
Kwon M, Song JY, Hwang JY, Seong SJ, Park KJ, Jo YT, Kim YJ, Ahn ME, Lee SK.   +8 more
europepmc   +1 more source

Inferring the decision rules that drive co-foraging affiliations in wild mixed-species parrot groups. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Ferdinand V, Pattenden E, Brightsmith DJ, Hobson EA.   +3 more
europepmc   +1 more source

DECISIONS AND RULINGS [PDF]

The Bulletin of the National Tax Association, 1924
openaire   +1 more source