Results 91 to 100 of about 36,161,252 (288)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Decision support in Down’s syndrome screening using multi-criteria decision analysis: a pilot study
Epidemiology, Biostatistics and Public Health, 2022 Background: the aim of the study was to develop and pilot use of a decision support system (DSS) to help women choose the option that best respects their personal values among the different screening/diagnostic tests for Down’s syndrome.
Anna Erenbourg +4 more
doaj
A comparison of student outcomes from an internet-based inventory simulation
, 2017 The increasing globalization and global integration of national economies suggests the necessity of developing pedagogy that infuses global content throughout the business school curriculum.
Bruce, Raymond C., Dempsey, Mary
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2014 Purpose: In Austria, the existing payment mechanism for ambulatory health care has a strong fee-for-service component. Due to legal requirements, however, Austrian sickness funds have to implement a new payment system with a focus on lump sum payment for
Pfeffer, N. +3 more
core +4 more sources
Structuring Intervention Decisions to Prevent Genocide and Mass Atrocities [PDF]
, 2015 8 pagesDrawing on techniques from decision analysis, psychology, and negotiation analysis, we highlight a general approach to assessing genocide prevention decisions that we believe could provide decision makers with additional insight, consistency ...
Gregory, Robin, Slovic, Paul
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Journal for Lesson and Learning StudiesThe low level of decision-making skills among students poses a significant challenge in elementary teacher education programs. This study aims to evaluate decision-making skills using the DECIDE model among elementary teacher education students in ...
Moh Salimi +6 more
doaj +1 more source