Results 151 to 160 of about 1,928,942 (329)

Managing Patient Health Across Diverse Spaces: Using Activity Theory to Model Pervasive Decision Support [PDF]

, 2012
Clinical decision support (CDS) systems can offer health care providers and patient data that is intelligently filtered and presented in ways to enhance diagnosis and long-term health care management, both within and outside clinical spaces.
Boston-Clay, Crystal, Downey, Michael, Faiola, Anthony, Jones, Josette, Newlon, Christine M.   +4 more
core  

Effects of machine learning-based clinical decision support systems on decision-making, care delivery, and patient outcomes: a scoping review

J. Am. Medical Informatics Assoc., 2023
A. Susanto, D. Lyell, Bambang Widyantoro, S. Berkovsky, F. Magrabi   +4 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Design of a goal ontology for medical decision-support [PDF]

, 2005
Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2005.Includes bibliographical references (leaves 34-36).Objectives: There are several ongoing efforts aimed at developing formal models of medical knowledge and reasoning to design ...
Zaccagnini, Davide
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Provider Perspectives on Sociotechnical Alignment of Intelligent Clinical Decision Support Systems

Information
Intelligent Clinical Decision Support Systems (ICDSS) are increasingly integrated into healthcare settings to enhance clinical decision-making, efficiency, and patient safety.
Andy Behrens, Cherie Noteboom, Patti Brooks   +2 more
doaj   +1 more source

A Relation Extraction Approach for Clinical Decision Support

, 2018
In this paper, we investigate how semantic relations between concepts extracted from medical documents can be employed to improve the retrieval of medical literature.
Agosti, Maristella, Di Nunzio, Giorgio Maria, Marchesin, Stefano, Silvello, Gianmaria   +3 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Clinical decision support systems (CDSS) in assistance to COVID‐19 diagnosis: A scoping review on types and evaluation methods

Health Science Reports
Background and Aims Due to the COVID‐19 pandemic, a precise and reliable diagnosis of this disease is critical. The use of clinical decision support systems (CDSS) can help facilitate the diagnosis of COVID‐19.
Arefeh Ameri, Atefeh Ameri, Farzad Salmanizadeh, Kambiz Bahaadinbeigy   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source