Results 121 to 130 of about 3,879,375 (275)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Optimizing Control of Wastewater Treatment Plant With Reinforcement Learning: Technical Evaluation of Twin-Delayed Deep Deterministic Policy Gradient Agent

open access: yesIEEE Access
Control of the wastewater treatment processes presents significant challenges due to the fluctuating nature of inflow and wastewater composition, alongside the system’s non-linear dynamics.
Zuzanna Klawikowska, Michal Grochowski
doaj   +1 more source

Evolution of Decision Support Systems Research Field in Numbers [PDF]

open access: yes
The scientific production in a certain field shows, in great extent, the research interests in that field. Decision Support Systems are a particular class of information systems which are gaining more popularity in various domains.
Ana-Maria SUDUC   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

THE DECISION SUPPORT SYSTEMS FOR THE INFORMATION SOCIETY (i-Society) [PDF]

open access: yes
The globalization process needs exact information flows that should be collected in due time. The Information Society ensures the communication between people with different expertise from various geographical areas that have similar interests.
Virgil Chichernea
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Assessment Methods for Building Energy Retrofits with Emphasis on Financial Evaluation: A Systematic Literature Review

open access: yesBuildings
The building sector remains one of the largest contributors to global energy consumption and CO2 emissions, yet selecting optimal retrofit strategies is often hindered by inconsistent evaluation practices and limited integration of environmental and ...
Maria D. Papangelopoulou   +2 more
doaj   +1 more source

Clinical Decision Support Systems [PDF]

open access: yes, 2011
Dinevski, Dejan   +4 more
openaire   +3 more sources

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