Results 121 to 130 of about 3,836,064 (302)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Restructuring and simplifying rule bases. [PDF]

open access: yes
Rule bases are commonly acquired, by expert and/or knowledge engineer, in a form which is well suited for acquisition purposes. When the knowledge base is executed, however, a different structure may be required. Moreover, since human experts normally do
Vanthienen, Jan, Wets, G, Dries, E
core  

Combining Naive Bayes and Decision Tables [PDF]

open access: yes, 2008
We investigate a simple semi-naive Bayesian ranking method that combine naive Bayes with induction of decision tables. Naive Bayes and decision tables can both be trained efficientyly, and the same holds true for the combined semi-naive model.
Hall, Mark A.   +3 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A Multi-Criteria Decision Framework for Animal Welfare Policy [PDF]

open access: yes
Policy decisions aimed at improving farm animal welfare involve balancing several competing objectives. Not only do such decisions involve tradeoffs between social, ethical, economic and welfare considerations, animal welfare itself is a multi ...
Hellstrom, J., Bicknell, Kathryn
core  

Use of Decision Tables to Simulate Management in SWAT+

open access: yes, 2018
Decision tables have been used for many years in data processing and business applications to simulate complex rule sets. Several computer languages have been developed based on rule systems and they are easily programmed in several current languages ...
Raghavan Srinivasan   +9 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

PCMDI/cmip6-cmor-tables: update to 01.00.15

open access: yes, 2017
JSON Tables for CMOR3 to create CMIP6 ...
Javier Vegas-Regidor   +3 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

CLUSTERING OF DECISION TABLES TOWARD ROUGH SET-BASED GROUP DECISION AID

open access: yes, 2011
In order to analyze the distribution of individual opinions (decision rules) in a group, clustering of decision tables is proposed. An agglomerative hierarchical clustering (AHC) of decision tables has been examined.
RYUTA ENOMOTO, MASAHIRO INUIGUCHI
core   +1 more source

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