Results 31 to 40 of about 979,707 (169)

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

On the Depth of Decision Trees with Hypotheses [PDF]

open access: yesEntropy, 2022
In this paper, based on the results of rough set theory, test theory, and exact learning, we investigate decision trees over infinite sets of binary attributes represented as infinite binary information systems. We define the notion of a problem over an information system and study three functions of the Shannon type, which characterize the dependence ...
openaire   +4 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

GENESIM : genetic extraction of a single, interpretable model [PDF]

open access: yes, 2016
Models obtained by decision tree induction techniques excel in being interpretable.However, they can be prone to overfitting, which results in a low predictive performance. Ensemble techniques are able to achieve a higher accuracy. However, this comes at
De Turck, Filip   +4 more
core   +2 more sources

P2P Domain Classification using Decision Tree

open access: yes, 2011
In Peer-to-Peer context, a challenging problem is how to find the appropriate peer to deal with a given query without overly consuming bandwidth? Different methods proposed routing strategies of queries taking into account the P2P network at hand.
Barbar, Aziz, Ismail, Anis
core   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

What are decision trees? [PDF]

open access: yesNature Biotechnology, 2008
Decision trees have been applied to problems such as assigning protein function and predicting splice sites. How do these classifiers work, what types of problems can they solve and what are their advantages over alternatives?
Carl Kingsford, Steven L. Salzberg
openaire   +3 more sources

Fully-Dynamic Decision Trees

open access: yesProceedings of the AAAI Conference on Artificial Intelligence, 2023
We develop the first fully dynamic algorithm that maintains a decision tree over an arbitrary sequence of insertions and deletions of labeled examples. Given ε>0 our algorithm guarantees that, at every point in time, every node of the decision tree uses a split with Gini gain within an additive ε of the optimum.
Bressan M., Damay G., Sozio M.
openaire   +2 more sources

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

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