Results 41 to 50 of about 785,617 (209)

Learning Multi-Tree Classification Models with Ant Colony Optimization [PDF]

open access: yes, 2014
Ant Colony Optimization (ACO) is a meta-heuristic for solving combinatorial optimization problems, inspired by the behaviour of biological ant colonies. One of the successful applications of ACO is learning classification models (classifiers).
Otero, Fernando E.B., Salama, Khalid M.
core   +1 more source

Comparative Analysis of Deterministic and Nondeterministic Decision Trees for Decision Tables from Closed Classes

open access: yesEntropy
In this paper, we consider classes of decision tables with many-valued decisions closed under operations of the removal of columns, the changing of decisions, the permutation of columns, and the duplication of columns.
Azimkhon Ostonov, Mikhail Moshkov
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Mixed-Integer Convex Nonlinear Optimization with Gradient-Boosted Trees Embedded [PDF]

open access: yes, 2019
Decision trees usefully represent sparse, high dimensional and noisy data. Having learned a function from this data, we may want to thereafter integrate the function into a larger decision-making problem, e.g., for picking the best chemical process ...
Krennrich, Gerhard   +4 more
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Prediction of survival probabilities with Bayesian Decision Trees [PDF]

open access: yes, 2013
Practitioners use Trauma and Injury Severity Score (TRISS) models for predicting the survival probability of an injured patient. The accuracy of TRISS predictions is acceptable for patients with up to three typical injuries, but unacceptable for patients
Bailey   +50 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Decision Stream: Cultivating Deep Decision Trees

open access: yes, 2017
Various modifications of decision trees have been extensively used during the past years due to their high efficiency and interpretability. Tree node splitting based on relevant feature selection is a key step of decision tree learning, at the same time ...
Ignatov, Andrey, Ignatov, Dmitry
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Decision trees: from efficient prediction to responsible AI

open access: yesFrontiers in Artificial Intelligence, 2023
This article provides a birds-eye view on the role of decision trees in machine learning and data science over roughly four decades. It sketches the evolution of decision tree research over the years, describes the broader context in which the research ...
Hendrik Blockeel   +6 more
doaj   +1 more source

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