Results 71 to 80 of about 3,593,349 (290)

On Explaining Decision Trees

open access: yesCoRR, 2020
Decision trees (DTs) epitomize what have become to be known as interpretable machine learning (ML) models. This is informally motivated by paths in DTs being often much smaller than the total number of features. This paper shows that in some settings DTs can hardly be deemed interpretable, with paths in a DT being arbitrarily larger than a PI ...
Yacine Izza   +2 more
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Causal Decision Trees [PDF]

open access: yesIEEE Transactions on Knowledge and Data Engineering, 2017
Uncovering causal relationships in data is a major objective of data analytics. Causal relationships are normally discovered with designed experiments, e.g. randomised controlled trials, which, however are expensive or infeasible to be conducted in many cases.
Jiuyong Li   +4 more
openaire   +3 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Complexity of Deterministic and Strongly Nondeterministic Decision Trees for Decision Tables From Closed Classes

open access: yesIEEE Access
This paper investigates classes of decision tables (DTs) with 0-1-decisions that are closed under the removal of attributes (columns) and changes to the assigned decisions to rows.
Azimkhon Ostonov, Mikhail Moshkov
doaj   +1 more source

Decision making with decision event graphs [PDF]

open access: yes, 2010
We introduce a new modelling representation, the Decision Event Graph (DEG), for asymmetric multistage decision problems. The DEG explicitly encodes conditional independences and has additional significant advantages over other representations of ...
Thwaites, Peter   +2 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Method of decision tree applied in adopting the decision for promoting a company

open access: yesAnnals of Spiru Haret University Economic Series, 2015
The decision can be defined as the way chosen from several possible to achieve an objective. An important role in the functioning of the decisional-informational system is held by the decision-making methods.
Cezarina Adina TOFAN
doaj   +1 more source

Machine Learning Methods with Decision Forests for Parkinson’s Detection

open access: yesApplied Sciences, 2021
Biomedical engineers prefer decision forests over traditional decision trees to design state-of-the-art Parkinson’s Detection Systems (PDS) on massive acoustic signal data.
Moumita Pramanik   +4 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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