Results 81 to 90 of about 5,778,654 (336)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

A case study for assessing the utility of a decision tree based learning algorithm in mental health inpatient care quality management

open access: yesEuropean Psychiatry, 2022
Introduction There is limited knowledge about the potential role of machine learning (ML) in quality improvement of psychiatric care. Objectives Our case study was to determine whether ML decision trees used on patient databases are suitable for ...
R. Wernigg, M. Wernigg
doaj   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

An anonymization technique using intersected decision trees

open access: yesJournal of King Saud University: Computer and Information Sciences, 2015
Data mining plays an important role in analyzing the massive amount of data collected in today’s world. However, due to the public’s rising awareness of privacy and lack of trust in organizations, suitable Privacy Preserving Data Mining (PPDM) techniques
Sam Fletcher, Md Zahidul Islam
doaj   +1 more source

Interpretable surrogate models to approximate the predictions of convolutional neural networks in glaucoma diagnosis

open access: yesMachine Learning: Science and Technology, 2023
Deep learning systems, especially in critical fields like medicine, suffer from a significant drawback, their black box nature, which lacks mechanisms for explaining or interpreting their decisions.
Jose Sigut   +4 more
doaj   +1 more source

Learning Optimal Decision Trees with SAT

open access: yesInternational Joint Conference on Artificial Intelligence, 2018
Explanations of machine learning (ML) predictions are of fundamental importance in different settings. Moreover, explanations should be succinct, to enable easy understanding by humans.
Nina Narodytska   +3 more
semanticscholar   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

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