Results 61 to 70 of about 4,394,320 (321)

Un sistema de información basado en costos Para la toma de decisiones sobre precios: Caso aplicado a una empresa mutiproductora del sector gastronómico

open access: yesEscritos Contables y de Administración, 2017
El presente trabajo se basa en un estudio de caso de una empresa gastronómica multiproductora cuya principal necesidad radica en poder identificar y cuantificar los costos de cada uno de los productos vendidos, así como también mejorar la forma en la ...
Antonela Perata   +2 more
doaj   +1 more source

RAZONES FINANCIERAS DE LIQUIDEZ EN LA GESTIÓN EMPRESARIAL PARA TOMA DE DECISIONES

open access: yes, 2017
Los indicadores financieros de liquidez son fundamentales para evaluar la situacion y el desempeno economico y financiero de una empresa a corto plazo, es decir, detectar si la empresa tiene suficientes recursos financieros y disponibles para cubrir las ...
Alex Humberto Herrera Freire   +4 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

El proceso de toma de decisiones profesionales a través del coaching

open access: yes, 2017
Resumen es: En este trabajo se afronta, de una forma comprensiva, el proceso de la toma de decisiones en la realidad del coaching.
M. A. González, Meritxell Obiols Soler
semanticscholar   +1 more source

The Decisional Environment Theoretical Aspects [PDF]

open access: yesSSRN Electronic Journal, 2009
The present paper speaks about the main theoretical aspects connected to the decisional environment. Thus, we defined the decision and its major role in the managerial process. Secondly we followed the stages and perception along time in defining the concept of decision.
openaire   +6 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Breves reflexiones en torno a la argumentación jurídica y su contexto

open access: yesArgumentos, 2021
El artículo hace foco en las razones paradigmáticas que marcan la importancia de la argumentación jurídica en el Estado de derecho actual. Para ello, se analiza la mutación en la comprensión del derecho, direccionada principalmente a la función que deben
Ruhl, Luciano Ulises
doaj   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Differences on Utilitarian and Moral Decision Between Male and Female

open access: yesPensamiento Psicológico, 2019
Objetivo. Los juicios morales se basan en decisiones que toman en cuenta la representación de las normas y la ley, los valores, la funcionalidad y la situación en sí.
César A. Acevedo-Triana   +2 more
doaj   +1 more source

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