Results 81 to 90 of about 368,305 (304)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Matemática para las decisiones financieras [Capítulo 1]

fondoeditorial@upc.edu.peEl texto introduce al alumno al mundo de las finanzas. Proporciona una serie de herramientas que permite el cálculo de resultados financieros, tanto de inversión como de financiamiento, para una toma razonable de decisiones ...
Chu Rubio, Manuel, Aguero Olivos, Carlos
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

¿Qué se valora del bosque nativo y cómo se pueden restaurar los agroecosistemas? Percepciones y preferencias de productores agrícola-ganaderos del Espinal, al sureste de Córdoba

Ecología Austral
Los agroecosistemas son socioecosistemas en los que las personas perciben, valoran y se benefician con los bienes y servicios que proporciona la naturaleza; además, la modifican en función de sus preferencias y decisiones.
Malena Villarruel Parma, Fernando Zamudio, Esteban Kowaljow   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

PROSPECTIVE AND SCORECARD, A STRATEGIC WEAPON AGAINST ENVIRONMENTAL CHANGES

Anuario Facultad de Ciencias Económicas y Empresariales, 2016
Until the decade of the 70 the nucleus of the concern in companie´s bussiness management was constituted it the achievement of the efficiency, a very important economic condition, but with the turbulence of the environment this condition was necessary ...
María del C. Herrero-Infante, Yanet Mora-Herrero   +1 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Variante del método promethee para decisiones multicriterio discretas

Costos y Gestión
Existen dos grandes divisiones en las situaciones de toma de decisiones con múltiples obje­tivos: programación multiobjetivo, referido a variables continuas, y decisiones multicriterio discretas. El trabajo se centra en la problemática de las decisiones
Raúl Alberto Ercole, Claudia Beatriz Peretto   +1 more
doaj   +1 more source

DECISIONE

, 2006
Voce della Enciclopedia filosofica a cura di V ...
PAGANI, Paolo, SEVERINO, Emanuele, MORANDO D.   +2 more
openaire   +1 more source