Results 61 to 70 of about 400,907 (299)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Tomar decisiones en la biblioteca pública contando con el ciudadano, una estrategia apenas utilizada [PDF]
, 2002 Publicad
Pacios Lozano, Ana Reyes
core +2 more sources
Toma de decisiones clínicas en atención primaria
Revista Médica Herediana, 2013 El profesional del primer nivel de atención necesita estar altamente calificado en tomar decisiones médicas con el debido respaldo científico, aplicado a una metodología ordenada y eficiente a la hora de tomar una decisión.
Antonio Moncada, María Sofía Cuba
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
LA ESTADISTICA Y LA COMPUTACION EN APOYO A LA TOMA DE DECISIONES
Ingeniería, 2011 La mayoria de la decisiones a nivel tactico-estrategico de una organizacion necesitan un apoyo computacional que ofrezca mas que simples datos descriptivos.
Vladimir Lara Villagrán +1 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Análisis de riesgos en proyectos de inversión
Pensamiento Crítico, 2009 En casi todos los proyectos privados utilizan conceptos como demanda, oferta, aversión al riesgo, etc.; sin embargo, pocas veces observamos la aplicación de instrumentos propios del análisis económico para evaluar estos aspectos.
Elias Sánchez Z.
doaj +1 more source
ALGUNOS MODELOS DE TOMA DE DECISIONES [PDF]
, 2012 Para las personas que toman decisiones, es difícil tener en cuenta todos los factores que inciden en la decisión, por tanto, es indispensable encontrar alguna forma de descomponer estos factores, de tal manera que le permita a los tomadores de ...
Jimenez Lozano, Guillermo +1 more
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source