Results 101 to 110 of about 24,911 (203)

Sequential decitabine and carboplatin treatment increases the DNA repair protein XPC, increases apoptosis and decreases proliferation in melanoma

BMC Cancer, 2018
Background Melanoma has two key features, an over-representation of UV-induced mutations and resistance to DNA damaging chemotherapy agents. Both of these features may result from dysfunction of the nucleotide excision repair pathway, in particular the ...
Timothy Budden, Andre van der Westhuizen, Nikola A. Bowden   +2 more
doaj   +1 more source

DNA methylation and trinucleotide repeat expansion diseases [PDF]

, 2012
Copyright @ 2012 InTechThis article has been made available through the Brunel Open Access Publishing Fund.This article is made available through the Brunel Open Access Publishing ...
Pook, M
core   +1 more source

Decitabine and trichostatin A : a synergistic combination in ALL [PDF]

, 2009
Dissertação de mestrado integrado em Medicina, apresentado á Faculdade de Medicina da Universidade de CoimbraInvestigações recentes demonstraram que a regulação epigenética da expressão génica envolve a metilação regiões CpG, assim como a desacetilação ...
Costa, Carlos
core  

Comparison of clinical efficacy between decitabine combined with half the amount of CAG regimen with CAG regimen alone in patients with inermediate to high-risk myelodysplastic syndrome

BIO Web of Conferences, 2017
Objective: To investigate the efficacy and safety of decitabine combined with half the amount of CAG and CAG regimen alone. Methods: Comparison the effectiveness, overall survival and incidence of adverse reactions of 42 cases of MDS used decitabine ...
Fan Zhenwei, Wang Xuan, Zhao Chunshan, Wang Wei, Yu Tingting   +4 more
doaj   +1 more source

A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation

Scientific Reports
The search for new approaches in cancer therapy requires a mechanistic understanding of cancer vulnerabilities and anti-cancer drug mechanisms of action.
Alex Y. Ge, Abolfazl Arab, Raymond Dai, Albertas Navickas, Lisa Fish, Kristle Garcia, Hosseinali Asgharian, Jackson Goudreau, Sean Lee, Kathryn Keenan, Melissa B. Pappalardi, Michael T. McCabe, Laralynne Przybyla, Hani Goodarzi, Luke A. Gilbert   +14 more
doaj   +1 more source

New lipid nanocapsules for decitabine encapsulation [PDF]

, 2016
Introduction: Currently decitabine, an antimetabolite agent is approved for acute myeloid leukemia in old patients and is administered via intra-venous (IV) route.
E. Roger, F. Lagarce, N. Lautram, T. Briot   +3 more
core  

TP53 and decitabine in acute myeloid leukemia and myelodysplastic syndromes [PDF]

, 2016
et al,, Fronick, C. C., Fulton, R. S., Ley, T. J., Miller, C. A., O\u27Laughlin, M., Petti, A. A., Wartman, L. D., Wilson, R. K.   +8 more
core   +2 more sources

Serendipity: Decitabine monotherapy induced complete molecular response in a 77-year-old patient with acute promyelocytic leukemia [PDF]

, 2019
Abboud, Camille N, Abboud, Ramzi, Cashen, Amanda F, DiPersio, John F, Duncavage, Eric J, Han, Se Young, Shirai, Cara Lunn, Welch, John S   +7 more
core   +3 more sources

Decitabine and Cedazuridine

American Journal of Health-System Pharmacy, 2020
openaire   +2 more sources

Economic Burden of Intravenous Decitabine Administration in Patients Affected by Acute Myeloid Leukemia Ineligible for Induction Chemotherapy and Impact of Oral Formulation Introduction: A Micro-Costing Study in Italy

ClinicoEconomics and Outcomes Research
Alessandra Di Costanzo, Luca Loreto, Chiara Vassallo, Francesca Fiorentino Real World Solutions, IQVIA Solutions Italy S.r.l., Milan, ItalyCorrespondence: Chiara Vassallo, Real World Solutions, IQVIA Solutions Italy s.r.l., Via Fabio Filzi 29, Milan ...
Di Costanzo A, Loreto L, Vassallo C, Fiorentino F   +3 more
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