Results 111 to 120 of about 18,818 (289)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Declarative and Procedural Knowledge in Teaching Grammar

open access: yes, 2010
When one has to teach a language, he should possess a vlew of whatlanguages. One possibility is to view language as a skill. Thereforelanguage learning is comparable to other types of cognitive skillacquisition.
Suroso, B. (Bambang)
core  

Influência de dois ambientes distintos de aprendizagem sobre o conhecimento tático declarativo de futebolistas da categoria sub-12

open access: yesRevista Brasileira de Futsal e Futebol, 2018
Atualmente o futebol vem sendo analisado cada vez mais de maneira cientifica, devido aos novos meios de pesquisas e treinamentos. Nesse contexto, torna-se importante avaliar o conhecimento tático de atletas de futebol.
Gabriel Marotta Magalhães   +3 more
doaj  

Efecto de los juegos reducidos sobre la coordinación, los CODA, la velocidad de tiro a portería y el conocimiento declarativo en jugadores de fútbol sub-12

open access: yesE-balonmano.com: Revista de Ciencias del Deporte
In recent years there has been a large increase in the number of investigations on small-sided games, however, this growth has not been the same for the study of small-sided games in formative stages.
Salvador Pérez-Muñoz   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Declarative Knowledge Discovery in Industrial Databases

open access: yes, 1997
Industry is increasingly overwhelmed by large-volume-data. For example, the pharmaceutical industry generates vast quantities of data both internally as a side-effect of screening tests and combinatorial chemistry, as well as externally from sources such
Stephen Muggleton
core  

Tactical critical thinking program on the tactical efficiency index, declarative and procedural knowledge in male soccer players: a case study

open access: yesFrontiers in Sports and Active Living
IntroductionThe purpose of this study was to explore the implications of the in-field implementation of a teaching strategy that promotes critical thinking (TPCT) on tactical ability, declarative, and procedural knowledge.
Samuel Jose Gaviria Alzate   +4 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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