Results 121 to 130 of about 76,673 (303)
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
On The Anisotropy Of Perceived Ground Extents And The Interpretation Of Walked Distance As A Measure Of Perception [PDF]
Two experiments are reported concerning the perception of ground extent to discover whether prior reports of anisotropy between frontal extents and extents in depth were consistent across different measures (visual matching and pantomime walking) and ...
Durgin, Frank H. +5 more
core +2 more sources
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Tables of Declination from Ptolemy to Regiomontanus
: The inclination of the path of the Sun in the sky with respect to the celestial equator, that is, the obliquity of the ecliptic, has been a major concern for astronomers since Antiquity.
Bernard R. Goldstein, José Chabás†
doaj +1 more source
Positioning and orienting a static cylindrical radio-reflector for wide field surveys
Several projects in radioastronomy plan to use large static cylindrical reflectors with an extended lobe sampling a sector of the rotating sky. This study provides the exact mathematical expression of the transit time of a celestial object within the ...
Moniez, Marc
core +1 more source
Decline of the Media? Decline of Democracy?
The media play a leading role in democracies. Their task is to enable citizens to make informed decisions by providing them with a balanced picture of the complex world. However, amongst journalists, the general knowledge of and interest in politics and EU affairs seems somewhat poor, which means that the media are not doing their job, and this is ...
openaire +1 more source
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source

