Results 81 to 90 of about 90,677 (316)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Calibration and Stokes Imaging with Full Embedded Element Primary Beam Model for the Murchison Widefield Array [PDF]
, 2017 15 pages, 11 figures. Accepted for publication in PASA. © Astronomical Society of Australia 2017The Murchison Widefield Array (MWA), located in Western Australia, is one of the low-frequency precursors of the international Square Kilometre Array (SKA ...
Bell, M. E. +24 more
core +4 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Sleepy Hollow, Village of and Municipal Employee Unit, United Federation of Police Officers [PDF]
, 2011 In the matter of the fact-finding between the Village of Sleepy Hollow, employer, and the United Federation of Police Officers, Municipal Employee Unit, union. PERB case no. M2009-266. Before: Peter A.
Korn, Peter A
core +1 more source
A Gaia-PS1-SDSS (GPS1) Proper Motion Catalog Covering 3/4 of the Sky
, 2017 We combine Gaia DR1, PS1, SDSS and 2MASS astrometry to measure proper motions for 350 million sources across three-fourths of the sky down to a magnitude of $m_r\sim20$\,.
Goldman, Bertrand +9 more
core +2 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Study on declination angle of diamond indenter on TiAl alloy nanoindentation
AIP AdvancesIn this paper, the molecular dynamics method is used to model TiAl alloy. The influence of the declination angle of the indenter on the nanoindentation of TiAl alloy is discussed.
Lijun Chen
doaj +1 more source
UK 2009-2010 repeat station report
Annals of Geophysics, 2013 The British Geological Survey is responsible for conducting the UK geomagnetic repeat station programme. Measurements made at the UK repeat station sites are used in conjunction with the three UK magnetic observatories: Hartland, Eskdalemuir and Lerwick,
Thomas J.G. Shanahan +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source