Results 101 to 110 of about 12,962 (271)
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
The impact of the COVID-19 pandemic on ICU clinical trials: a description of one research team's experience. [PDF]
Trials, 2023 Chlan LL +4 more
europepmc +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Introduction: Ten Trips Around the Conceptual Galaxy of Otherness
Rivista di Estetica, 2014 In introducing the present issue, we make clear that the concept of the other is susceptible to so multifarious declinations that it actually forms a conceptual galaxy. It is precisely this galaxy that the ten essays in the issue aim to shed light on. We
Massimo Dell’Utri, Stefano Caputo
doaj
A comparative history of childhood: Current research perspectives
Ricerche di Pedagogia e DidatticaThis set of reflections aims to indicate some possible paths, to be followed in the field of comparative education, which might contribute to defining the idea of childhood and to seeking the best form of educational care for children in the context of a
Carla Callegari
doaj +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
I principi del pragmatismo pedagogico di Tsunesaburo Makiguchi
Studi sulla FormazioneThe pedagogical pragmatism of Makiguchi (1871-1944), a Japanese primary school teacher and first inspirer of the lay Buddhist association Soka Gakkai, was developed as opposition to the Japanese nationalism of the early twentieth century, that was ...
Andrea Spano
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source