Results 71 to 80 of about 950 (265)
Architecture and narration: the architect as storyteller?
Since we are deeply involved in the era of communication, the interest in the relationship between architecture and forms of narration is not surprising.
Giusi Scavuzzo
doaj +1 more source
The impact of the COVID-19 pandemic on ICU clinical trials: a description of one research team's experience. [PDF]
Chlan LL +4 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Origins of Mesoamerican astronomy and calendar: Evidence from the Olmec and Maya regions. [PDF]
Šprajc I, Inomata T, Aveni AF.
europepmc +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
On January 1948, with the establishment of Center for Methodological Studies of Torino, the project of the unification of the methodology took shape. It was successfully initiative whom added many supporters inside the scientific and cultural field. Upon
Francesco Forleo
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Introduction: Ten Trips Around the Conceptual Galaxy of Otherness
In introducing the present issue, we make clear that the concept of the other is susceptible to so multifarious declinations that it actually forms a conceptual galaxy. It is precisely this galaxy that the ten essays in the issue aim to shed light on. We
Massimo Dell’Utri, Stefano Caputo
doaj

