Results 131 to 140 of about 103,505 (332)

Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain

open access: yesAdvanced Science, EarlyView.
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio   +3 more
wiley   +1 more source

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang   +12 more
wiley   +1 more source

Interference-Based Decode and Forward Scheme Using Relay Nodes in Heterogeneous Networks

open access: yesInternational Journal of Antennas and Propagation, 2012
This paper proposes interference-based decode and forward scheme that utilizes relay stations (RSs). In Long-Term-Evolution (LTE-) Advanced, heterogeneous networks in which femto- and picocells are overlaid onto macrocells are extensively discussed ...
Kentaro Nishimori   +2 more
doaj   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo   +10 more
wiley   +1 more source

Flow Decomposition for Multi-User Channels - Part I

open access: yes, 2018
A framework based on the idea of flow decomposition is proposed to characterize the decode-forward region for general multi-source, multi-relay, all-cast channels with independent input distributions. The region is difficult to characterize directly when
Ponniah, Jonathan, Xie, Liang-Liang
core  

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

open access: yesAdvanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang   +11 more
wiley   +1 more source

Jointed LDPC codes design for half-duplex relay channels

open access: yesTongxin xuebao, 2013
In order to increase the coding gain of decode-and-forward half-duplex relay channel, a jointed LDPC coding structure and its corresponding optimization scheme was proposed. Novel structure made the subcodes of both source and relay nodes as parts of the
Zi-qiang CHEN   +3 more
doaj   +2 more sources

Improved Polar selective decoding and forwarding cooperation

open access: yesDianxin kexue, 2020
An improved Polar selective decoding and forwarding (IPSDF) scheme based on cooperative threshold de-cision was proposed.Firstly,a new construction of Polar codes according to the fading channel state information (CSI) was proposed.Then,a relay with best CSI was selected from the candidate relay set as the best relay.In addition,the proposed Polar ...
Qichao SUN   +5 more
openaire   +2 more sources

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

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