Results 131 to 140 of about 5,219,664 (202)

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Deep Lidar-Guided Image Deblurring. [PDF]

Sensors (Basel)
Yi Z, Valsesia D, Bianchi T, Magli E.
europepmc   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Application of Information Theory to Computer Vision and Image Processing II. [PDF]

Entropy (Basel)
Flores-Fuentes W, Sergiyenko O, Rodríguez-Quiñonez JC, Miranda-Vega JE.   +3 more
europepmc   +1 more source

Electrical Resistivity Tomography for the 2D and 3D Investigation of Pingos and Permafrost Mounds in Northern Canada's Mountain and Coastland Areas

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Pingos and related permafrost mounds are widespread periglacial landforms in Arctic environments that are ice‐rich on the one hand and contain taliks on the other, making them vulnerable to climate change. So far, the interior, geophysical characteristics, and distribution of ground ice within these dome‐ or cone‐shaped features have not been ...
Tim Wiegand, Julius Kunz, Christof Kneisel   +2 more
wiley   +1 more source

DFINE-PFM: a real-time instance segmentation network for potato harvester conveyor belts. [PDF]

Front Plant Sci
Zhang Q, Mo X, Zhang H, Li W, Liu G, Yang R, Pan Z.   +6 more
europepmc   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

Validation of a Markerless Non-Contact Gait Analysis System for Three-Dimensional Gait Kinematics in Patients with Ankle Injuries: A Concurrent Comparison Study with the Vicon Three-Dimensional Motion Capture System. [PDF]

Sensors (Basel)
Cao X, Zhou Q, Wang S, Dong M, Ren S, Guo Q.   +5 more
europepmc   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

SVRS: self-supervised 3D voxel reconstruction network from stereo vision. [PDF]

Sci Rep
Zou Z, Wu Y, Zhang H, Xu Q, Wang R.
europepmc   +1 more source