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RNAi Degrades the SARS-CoV-2 Spike Protein RNA for Developing Drugs to Treat COVID-19

open access: yesNano Biomedicine and Engineering, 2022
COVID-19 is caused by severe acute respiratory SARS-CoV-2. Regardless of the availability of treatment strategies for COVID-19, effective therapy will remain essential.
Weiwei Zhang   +17 more
doaj   +1 more source

Differential molecular response in mice and human thymocytes exposed to a combined-dose radiation regime

open access: yesScientific Reports, 2022
In the quest for more effective radiation treatment options that can improve both cell killing and healthy tissue recovery, combined radiation therapies are lately in the spotlight.
Pilar López-Nieva   +8 more
doaj   +1 more source

Patterns of Differentially Expressed circRNAs in Human Thymocytes

open access: yesNon-Coding RNA, 2022
Circular RNAs (circRNAs) are suggested to play a discriminative role between some stages of thymocyte differentiation. However, differential aspects of the stage of mature single-positive thymocytes remain to be explored.
Pilar López-Nieva   +7 more
doaj   +1 more source

Quantifying telomeric lncRNAs using PNA-labelled RNA-Flow FISH (RNA-Flow)

open access: yesCommunications Biology, 2022
Telomeric-associated long non-coding RNAs TERRA and TERC can be quantified in culture cell lines and human PBMCs using peptide nucleic acid probes with flow cytometry (RNA-Flow).
Iria González-Vasconcellos   +4 more
doaj   +1 more source

Time-to-Digital Converter IP-Core for FPGA at State of the Art

open access: yesIEEE Access, 2021
The Field Programmable Gate Array (FPGA) structure poses several constraints that make the implementation of complex asynchronous circuits such as Time–Mode (TM) circuits almost unfeasible.
Fabio Garzetti   +3 more
doaj   +1 more source

Mechanical hierarchy in the formation and modulation of cortical folding patterns

open access: yesScientific Reports, 2023
The important mechanical parameters and their hierarchy in the growth and folding of the human brain have not been thoroughly understood. In this study, we developed a multiscale mechanical model to investigate how the interplay between initial ...
Poorya Chavoshnejad   +6 more
doaj   +1 more source

Revisiting Persistent Neuronal Activity During Covert Spatial Attention

open access: yesFrontiers in Neural Circuits, 2021
Persistent activity has been observed in the prefrontal cortex (PFC), in particular during the delay periods of visual attention tasks. Classical approaches based on the average activity over multiple trials have revealed that such an activity encodes ...
Julian L. Amengual, Suliann Ben Hamed
doaj   +1 more source

ZEM: Zero-Cycle Bit-Masking Module for Deep Learning Refresh-Less DRAM

open access: yesIEEE Access, 2021
In sub-20 nm technologies, DRAM cells suffer from poor retention time. With the technology scaling, this problem tends to be worse, significantly increasing refresh power of DRAM.
Duy-Thanh Nguyen   +4 more
doaj   +1 more source

Hacia una caracterización de los traductores e intérpretes en Colombia

open access: yesIkala: Revista de Lenguaje y Cultura, 2020
El objetivo principal de este estudio, de carácter exploratorio, metodología cuantitativa y enfoque descriptivo, fue realizar una caracterización de los traductores e intérpretes en Colombia.
John Jairo Giraldo-Ortiz   +4 more
doaj   +1 more source

A Robust Screen-Free Brain-Computer Interface for Robotic Object Selection

open access: yesFrontiers in Robotics and AI, 2020
Brain signals represent a communication modality that can allow users of assistive robots to specify high-level goals, such as the object to fetch and deliver.
Henrich Kolkhorst   +9 more
doaj   +1 more source

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