Results 41 to 50 of about 213,998 (288)
The Encoding / Decoding Model on Keats’s “Ode on a Grecian Urn” as a Thing
K@ta: A Biannual Publication on the Study of Language and Literature, 2016 John Keats, a main figure in the second generation of Romantic poets, was not generally well received by his contemporary critics, though during the course of time, he has become one of the most beloved poets.
Hussein Salimian Rizi, Pyeaam Abbasi
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Decoding Inner Speech Using Electrocorticography: Progress and Challenges Toward a Speech Prosthesis
Frontiers in Neuroscience, 2018 Certain brain disorders resulting from brainstem infarcts, traumatic brain injury, cerebral palsy, stroke, and amyotrophic lateral sclerosis, limit verbal communication despite the patient being fully aware.
Stephanie Martin +6 more
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Discrete Applied Mathematics, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
VINCENTI, Rita, H. J. KROLL
openaire +4 more sources
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Nature CommunicationsElucidating the spatial organization and functional specialization of immune cells within complex tissues remains challenging. We present UCASpatial, an ultra-precision spatial transcriptomics deconvolution algorithm utilizing entropy-based weighting to ...
Yin Xu +20 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
eLife, 2018 The anterior cingulate cortex (ACC) encodes information supporting mnemonic and cognitive processes. We show here that a rat’s position can be decoded with high spatiotemporal resolution from ACC activity.
Ali Mashhoori +4 more
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source