Results 61 to 70 of about 245,018 (286)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

How Morphology, Context, Vocabulary and Reading Shape Lexical Inference in Typical and Dyslexic Readers

open access: yesEducation Sciences
Children’s ability to infer meanings of unfamiliar words during reading is thought to rely on the interplay between decoding, morphological awareness, contextual support, and vocabulary knowledge, but it remains unclear how these sources operate in ...
Ifigeneia Dosi
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Decoding the Jewels: Renaissance Jewellery in Scotland [Book review]

open access: yes
A book review of, Decoding the Jewels: Renaissance Jewellery in Scotland, edited by Dr Anna Groundwater (2024).
Westland, Karen
core   +3 more sources

Supporting transition or playing catch-up in Grade 4? Implications for standards in education and training

open access: yesPerspectives in Education, 2014
This paper describes an intervention programme that was originally intended to support transition to English as language of learning and teaching (LoLT) in Grade 4 in a township school, using a pre- and post-test design.
Elizabeth J. Pretorius
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Exploring the Effects of Culturally Responsive Instruction on Reading Comprehension, Language Comprehension, and Decoding with Bayesian Multilevel Models

open access: yesEducation Sciences
Reading comprehension (RC) can be predicted from language comprehension (LC) and decoding, and all three constructs are responsive to structured teaching.
Jeanne Sinclair
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Graph-Based Codes and Iterative Decoding [PDF]

open access: yes, 2003
The field of error correcting codes was revolutionized by the introduction of turbo codes in 1993. These codes demonstrated dramatic performance improvements over any previously known codes, with significantly lower complexity.
Khandekar, Aamod Dinkar
core   +1 more source

Ribosome•RelA structures reveal the mechanism of stringent response activation

open access: yeseLife, 2016
Stringent response is a conserved bacterial stress response underlying virulence and antibiotic resistance. RelA/SpoT-homolog proteins synthesize transcriptional modulators (p)ppGpp, allowing bacteria to adapt to stress.
Anna B Loveland   +6 more
doaj   +1 more source

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