Results 111 to 120 of about 65,270 (216)

The Prevalence and Risk Factors for at‐Risk MASH and Advanced Liver Fibrosis in People With Metabolic Risk Factors in Primary Care

Alimentary Pharmacology &Therapeutics, EarlyView.
This cross‐sectional study of 84 general practices found 24.3% had At‐Risk MASH defined by FNI > 0.30, and 4.3% had advanced fibrosis defined by FIB‐4 > 2.67. Diabetes and socio‐economic disadvantage were strong predictors of significant liver disease.
Leon A. Adams, Shaoke Lei, Luis Calzadilla‐Bertot, Silja Schrader, Sophie Frear, Chian Zhou, Sarah E. Heywood, Jon Emery   +7 more
wiley   +1 more source

High-Dose L-Serine Supplementation During Febrile Decompensation in <i>SARS1</i> Deficiency: A Case Report and Review of the Literature. [PDF]

JIMD Rep
Valle VA, Wiedemnan A, Feigerlova E, Coelho D, Jeannesson E, Rotaru I, Merten M, Raharimanana A, Feillet F, Ravel JM.   +9 more
europepmc   +1 more source

Clinical Burden of Symptomatic HEV‐3 Infection in Southern Spain

Alimentary Pharmacology &Therapeutics, EarlyView.
Clinical burden of symptomatic HEV‐3 infection in southern Spain. Between 2022 and 2025, 1124 patients with acute hepatitis, defined as ALT ≥ 3 times the upper limit of normal and negative screening for HAV, HBV, HCV, EBV and CMV, were evaluated in Andalusia.
María Casares‐Jimenez, Claudia Ferreira‐Tata, Isabel Viciana, Carolina Freyre‐Carrillo, Pedro Lopez‐Lopez, Ana Belen Perez, Berta Becerril‐Carral, Ana Fuentes, Juan Macías, Lucia Rios‐Muñoz, Francisco Franco‐Alvarez de Luna, María Teresa Cabezas‐Fernandez, Diana Corona‐Mata, Antonio Rivero‐Juarez, Antonio Rivero   +14 more
wiley   +1 more source

Late-onset bullous keratopathy after iris-fixated phakic intraocular lens implantation: a case report. [PDF]

BMC Ophthalmol
Ferrand S, Bogdanova-Bennett A, Cornelius DT, Ferrand RA.   +3 more
europepmc   +1 more source

From a novel pathogenic SAMD9L variant to cohort‐wide insights: Whole‐genome sequencing highlights somatic genetic rescue and phenotypic heterogeneity

British Journal of Haematology, EarlyView.
Summary Germline gain‐of‐function variants in sterile alpha motif domain–containing 9‐like (SAMD9L), located on chromosome 7q, cause a multisystem disorder characterized by bone marrow failure, immunodeficiency and variable neurological involvement. Disease evolution is frequently shaped by somatic genetic rescue (SGR), most commonly through monosomy 7,
Hadjer Dellal, Roman Klifa, Lise Larcher, Marie Passet, Tristan Celse, Laetitia Gouas, Maud Tusseau, AURAGEN Consortium, Alexis Praga, Virginie Bernard, Mathieu Fusaro   +10 more
wiley   +1 more source

Prognostication of Liver Disease Patients via the WFUMB 'Rule-of-4' Algorithm Using SSI-2D-SWE-Based Liver Stiffness Measurement. [PDF]

Liver Int
Sebesta C, Kramer G, Dominik N, Hofer BS, Balcar L, Thöne P, Jachs M, Hartl L, Simbrunner B, Schöchtner T, Haimberger F, Balutsch N, Stättermayer AF, Trauner M, Mandorfer M, Reiberger T, Bauer DJM.   +16 more
europepmc   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Progression of MASH to cirrhosis, decompensation, and mortality, and the utility of NITs for detection and risk stratification. [PDF]

Hepatol Commun
Newsome PN, Sartini C, Morris HL, Gazis D, Mospan AR, Barritt AS, Fried MW, Augustin S, Fraessdorf M, Rudolph B, Loomba R, Sanyal A, TARGET-NASH Investigators.   +12 more
europepmc   +1 more source

Ray‐Tracing‐Based Intraocular Lens Power Calculation in Combined Cataract Surgery and Descemet Membrane Endothelial Keratoplasty

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To compare the predictive accuracy of ray tracing‐based intraocular lens (IOL) power calculation formulas with the Barrett Universal II (BUII) formula in eyes with Fuchs endothelial corneal dystrophy (FECD) undergoing combined cataract surgery and Descemet membrane endothelial keratoplasty (triple DMEK).
Jan O. Weber, Klemens P. Kaiser, Jascha A. Wendelstein, H. Burkhard Dick, Thomas Kohnen, Ingo Schmack   +5 more
wiley   +1 more source

Sodium-Glucose Cotransporter 2 Inhibitors Versus Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes Mellitus and Liver Cirrhosis: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Shetty USA, Batool AE, Postoev A, Mohammed Abdul RH, Chaudhary S, Jabeen S, Wei CR, Amin A.   +7 more
europepmc   +1 more source