Results 1 to 10 of about 1,322,013 (311)

Endothelin-1 in portal hypertension: The intricate role of hepatic stellate cells

Experimental biology and medicine, 2020
Portal hypertension is one of the most important cirrhosis-associated complications of chronic liver disease, leading to significant morbidity and mortality.
D. Ezhilarasan
semanticscholar   +1 more source

Nonalcoholic fatty liver disease and portal hypertension

Exploration of Medicine, 2020
Nonalcoholic fatty liver disease (NAFLD) is a substantial and growing problem worldwide and has become the second most common indication for liver transplantation as it may progress to cirrhosis and develop complications from portal hypertension ...
M. Ryou, N. Stylopoulos, G. Baffy
semanticscholar   +1 more source

Features of encephalopathy diagnosis in patients with portal hypertension syndrome

Gastroenterologìa, 2017
Background. Hepatic encephalopathy is a pathological change in the brain functions of non-inflammatory origin, which is manifested by a syndrome of secondary neurological and cognitive disorders caused by a set of deep metabolic disorders, as a result of
Yu.M. Stepanov, N.V. Chaliy, S.L. Меlanich   +2 more
doaj   +1 more source

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Gastroenterology, 2019
Background & Aims: Mechanical forces contribute to portal hypertension (PHTN) and fibrogenesis. We investigated the mechanisms by which forces are transduced by liver sinusoidal endothelial cells (LSECs) into pressure and matrix changes.
M. Hilscher, Tejasav S. Sehrawat, J. Arab, Zhutian Zeng, Jinhang Gao, Mengfei Liu, Enis Kostallari, Yandong Gao, Douglas A. Simonetto, Usman Yaqoob, Sheng Cao, A. Revzin, A. Beyder, Rong A. Wang, P. Kamath, P. Kubes, V. Shah   +16 more
semanticscholar   +1 more source

Noninvasive Evaluation of Portal Hypertension: Emerging Tools and Techniques

International Journal of Hepatology, 2012
Portal hypertension is the main cause of complications in patients with cirrhosis. However, evaluating the development and progression of portal hypertension represents a challenge for clinicians.
V. K. Snowdon, N. Guha, J. A. Fallowfield   +2 more
doaj   +1 more source

Portal‐hypertensive gastropathy

Journal of Gastroenterology and Hepatology, 1998
ABSTRACTIn the present article we describe updated information concerning the clinical feature of portal‐hypertensive gastropathy (PHG), which is characterized by mucosal and submucosal vascular dilatation without inflammation. Although this lesion represents non‐variceal bleeding, there is a wide variation of its prevalence.
TOYONAGA, Atsushi, IWAO, Tadashi
openaire   +3 more sources

Portal Hypertension and Related Complications: Diagnosis and Management

Mayo Clinic proceedings, 2019
&NA; Portal hypertension is a major complication of cirrhosis, and its consequences, including ascites, esophageal varices, hepatic encephalopathy, and hepatorenal syndrome, lead to substantial morbidity and mortality.
Douglas A. Simonetto, Mengfei Liu, P. Kamath   +2 more
semanticscholar   +1 more source

Burden of pulmonary hypertension in patients with portal hypertension in the United States: a retrospective database study

Pulmonary Circulation, 2020
Patients with portal hypertension may develop pulmonary hypertension. The economic implications of these comorbidities have not been systematically assessed. We compared healthcare resource utilization and costs in the United States between patients with
Sandeep Sahay, Yuen Tsang, Megan Flynn, Peter Agron, Robert Dufour   +4 more
doaj   +1 more source

Splenic vein stenting for recurrent chylous ascites in sinistral portal hypertension: a case report

CVIR Endovascular, 2021
Background Sinistral portal hypertension results from obstruction or stenosis of the splenic vein and is characterized by normal portal vein pressures and liver function tests.
Brian Covello, Jacob Miller, Roberto Fourzali   +2 more
doaj   +1 more source

Pathophysiology of Portal Hypertension [PDF]

Clinics in Liver Disease, 1964
Portal hypertension is a major complication of liver disease that results from a variety of pathologic conditions that increase the resistance to the portal blood flow into the liver. As portal hypertension develops, the formation of collateral vessels and arterial vasodilation progresses, which results in increased blood flow to the portal circulation.
openaire   +2 more sources