Results 11 to 20 of about 1,322,013 (311)

Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapyKey points

open access: yesJHEP Reports, 2021
Summary: Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the dysregulation of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells ...
Yasuko Iwakiri, Jonel Trebicka
doaj   +2 more sources

Portal Hypertension

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2018
Mingyu Sun   +3 more
doaj   +3 more sources

Baveno VII – Renewing consensus in portal hypertension

open access: yesJournal of Hepatology, 2021
Summary To expand on the work of previous meetings, a virtual Baveno VII workshop was organised for October 2021. Among patients with compensated cirrhosis or compensated advanced chronic liver disease (cACLD – defined at the Baveno VI conference), the ...
R. de Franchis   +65 more
semanticscholar   +1 more source

Restoration of Bile Outflow in Case of Damage to Hepaticocholedochus and Failure of the Biliary Anastomosis After Laparoscopic Cholecystectomy

open access: yesНеотложная медицинская помощь, 2022
The aspect of injuring bile ducts during laparoscopic cholecystectomy is still of current concern. Causes of this complication include insufficient experience of surgical team, poor knowledge of topographic anatomy of subhepatic space, particularly when ...
A. V. Novozhilov   +2 more
doaj   +1 more source

Accuracy of spleen stiffness measurement for the diagnosis of clinically significant portal hypertension in patients with compensated advanced chronic liver disease: a systematic review and individual patient data meta-analysis.

open access: yesThe Lancet Gastroenterology and Hepatology, 2023
BACKGROUND The diagnosis of clinically significant portal hypertension is crucial for prognosis and treatment guidance in patients with compensated advanced chronic liver disease (ACLD).
E. Dajti   +19 more
semanticscholar   +1 more source

Pathophysiology and management of liver cirrhosis: from portal hypertension to acute-on-chronic liver failure

open access: yesFrontiers in Medicine, 2023
Cirrhosis transcends various progressive stages from compensation to decompensation driven by the severity of portal hypertension. The downstream effect of increasing portal hypertension severity leads to various pathophysiological pathways, which result
R. Jagdish   +7 more
semanticscholar   +1 more source

The Role of the Spleen in Portal Hypertension.

open access: yesJournal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2023
As liver disease progresses, intrahepatic vascular resistance increases (backward flow theory of portal hypertension) and collateral veins develop. Adequate portal hypertension is required to maintain portal flow into the liver through an increase in ...
H. Yoshida   +8 more
semanticscholar   +1 more source

Extrahepatic Surgery in Cirrhosis Significantly Increases Portal Pressure in Preclinical Animal Models

open access: yesFrontiers in Physiology, 2021
Background: Liver cirrhosis is a relevant comorbidity with increasing prevalence. Postoperative decompensation and development of complications in patients with cirrhosis remains a frequent clinical problem.
Johannes Chang   +21 more
doaj   +1 more source

North American Practice-Based Recommendations for Transjugular Intrahepatic Portosystemic Shunts in Portal Hypertension

open access: yesClinical Gastroenterology and Hepatology, 2021
Complications of portal hypertension, including ascites, gastrointestinal bleeding, hepatic hydrothorax, and hepatic encephalopathy are associated with significant morbidity and mortality.
J. Boike   +29 more
semanticscholar   +1 more source

Machine learning prediction model for post- hepatectomy liver failure in hepatocellular carcinoma: A multicenter study

open access: yesFrontiers in Oncology, 2022
IntroductionPost-hepatectomy liver failure (PHLF) is one of the most serious complications and causes of death in patients with hepatocellular carcinoma (HCC) after hepatectomy. This study aimed to develop a novel machine learning (ML) model based on the
Jitao Wang   +23 more
doaj   +1 more source

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