Results 171 to 180 of about 99,760 (303)

Sarcopenia Is Associated With Mortality and Progression of Cirrhosis in Decompensated but Not Compensated Disease—A Multicentre Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a retrospective cohort of 1,624 adults with cirrhosis, sarcopenia was independently associated with unplanned hospitalization, death, and cirrhosis progression (or death) in patients with decompensated disease. In compensated cirrhosis, sarcopenia was associated only with a higher risk of unplanned hospitalization.
Puneeta Tandon, Sarah Wang, Moon Young Kim, Bart Van Hoek, Daphne Bot, Jeroen L. A. van Vugt, Berend Beumer, Jan Ijzermans, Sunil Taneja, Ajay Duseja, Surender Singh, Maryam Ebadi, Aldo J. Montano‐Loza   +12 more
wiley   +1 more source

From Cure to Complexity: Post-SVR Liver and Metabolic Trajectories in Diabetic Patients. [PDF]

Liver Int
Asero C, Franzè MS, Maltese T, La Spada A, Lombardo D, Grisanti C, Russo G, Giandalia A, Pitrone C, Filomia R, Caccamo G, Saitta C, Licata A, Pollicino T, Cacciola I.   +14 more
europepmc   +1 more source

Correlation of Bile Acid Dynamics to Bulevirtide Response and Disease Severity in Patients With Hepatitis D

Alimentary Pharmacology &Therapeutics, EarlyView.
Bulevirtide increases bile acid levels in most patients; however, changes in bile acids do not predict virological response or adverse events, nor do they reflect treatment adherence. After discontinuation of bulevirtide, bile acid levels rapidly decline.
Marlene Hintersteininger, Michael Schwarz, Philipp Schwabl, Lukas Hartl, Lorenz Balcar, Benedikt Silvester Hofer, Georg Kramer, Christian Sebesta, Paul Thöne, Patrik Attalla, Michael Gschwantler, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Mathias Jachs   +14 more
wiley   +1 more source

The rate and predictors of recompensation in patients with decompensated cirrhosis due to metabolic dysfunction-associated liver disease (MASLD). [PDF]

Hepatol Commun
Jiménez-Masip A, Broquetas MT, Muñoz-Martinez S, Serra-Matamala I, Rojo D, Sòria A, El Maimouni C, Pagès L, Pons M, Carrión JA, Ginès P, Genescà J, Graupera I, Pericàs JM.   +13 more
europepmc   +1 more source

Recompensation following first decompensation in patients with alcohol-related cirrhosis. [PDF]

BMC Gastroenterol
Kwak JY, Jeon H, Kwon HU, Kim JE, Han JH, Choi JW, Cha RR, Lee JM, Lee SS.   +8 more
europepmc   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Post-Bleed Prognosis Beyond Hospitalization: The CLIF Consortium Acute Decompensation Score (CLIF-C AD) Predicts Six-Week Mortality After Upper Gastrointestinal Bleeding in Patients With Cirrhosis. [PDF]

Cureus
Ciorba IM, Craciun Ciorba N, Bataga SM.
europepmc   +1 more source

Mechanism of Cardiac Arrest in Fatal Anaphylaxis

Clinical &Experimental Allergy, EarlyView.
This population‐based retrospective cohort study of clinical deterioration in anaphylaxis deaths identifies bronchospasm as the preponderant cause of cardiac arrest, especially in food and drug allergen exposures. The clinical implication is that anaphylaxis guidelines require appropriate emphasis on respiratory involvement and treatment to prevent ...
Ben A. McKenzie, Stuart D. Marshall, Lena A. Sanci, Catriona Moynihan, Chris Selman, Jo A. Douglass   +5 more
wiley   +1 more source

Clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, EarlyView.
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara, Minna Kraatari‐Tiri, Jussi‐Pekka Tolonen, Marko Merikukka, IDGEN Study Group, Hannaleena Kokkonen, Teija Paakkola, Susanna Varis, Antti Dahl, Jarmo Körkkö, Jonna Komulainen‐Ebrahim, Jukka Moilanen, Johanna Uusimaa, Outi Kuismin, Elisa Rahikkala   +14 more
wiley   +1 more source

Fibrosis activity <i>vs</i>. disease stage: Complementary and independent predictors of outcomes in alcohol-related liver disease. [PDF]

JHEP Rep
Johansen S, Israelsen M, Thorhauge KH, Hansen JK, Hansen CD, Schnefeld HL, Andersen P, Villesen I, Bech KT, Detlefsen S, Torp N, Leeming D, Thiele M, Krag A, Karsdal M, GALAXY consortia.   +15 more
europepmc   +1 more source