Results 171 to 180 of about 65,270 (216)

Pathomechanism of Fever‐Induced Liver Failure in NBAS Deficiency and Treatment Effect of NAC—Observations In Vitro and In Vivo

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims Pathogenic variants in neuroblastoma amplified sequence (NBAS) gene causes infantile liver failure type 2 (IFLS2; MIM 616483), characterised by recurrent episodes of liver failure triggered by febrile infections. The underlying pathophysiological mechanisms remain incompletely understood. With this work we try to shed light
Tian Sun, Nicole Hammann, Lina Leghlam, Bianca Peters, Cigdem Arikan, Sarah M. Bedoyan, Qian Chen, Tal Dattner, Felix Distelmaier, Alexander Fichtner, Sven F. Garbade, Nedim Hadžić, Robert Hegarty, Andrea Hellwig, Marianne Hørby Jørgensen, Carolin Jentsch, Sabine Jung‐Klawitter, Martin Laass, Elke Lainka, Hannah Münch, Halise Neslihan Önenli Mungan, Moritz Niesert, Stephanie Oehrl, Begona Polo, Knut Schäkel, James E. Squires, Stefan Kölker, Georg F. Hoffmann, Christian Staufner, Dominic Lenz   +29 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Reply: Rethinking sustained recompensation in MASLD cirrhosis: The value of pharmacological maintenance. [PDF]

Hepatol Commun
Jiménez-Masip A, Pulido JMP.
europepmc   +1 more source

Epidemiological and Clinical Profile of Heart Failure at the Morafeno University Hospital of Toamasina, Madagascar: A Three-Year Retrospective Study. [PDF]

Cureus
Rakoto Sedson RO, Bezara JC, Ranaivoson HMS, Nomenjanahary MH, Randriamihangy NA, Rabearivony N, Rakotoarimanana S.   +6 more
europepmc   +1 more source

Hepatic Glycogen Storage Diseases in Brazil: A Multicenter Study

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1591-1600, July 2026.
ABSTRACT To describe clinical and laboratory characteristics, emphasizing the evolution of patients with hepatic glycogen storage diseases (GSDs) followed in Brazilian reference centers. Multicenter, retrospective study involving 13 centers, using RedCap platform. 132 patients were included: 63 (47.8%) GSD type I (56 Ia, 7 Ib), 13 (9.8%) with type III (
Mariana Pena Costa, Alexandre Rodrigues Ferreira, Adriana Teixeira Rodrigues, Rodrigo Rezende Arantes, Thais Costa Nascentes Queiroz, Elisa de Carvalho, Gilda Porta, Irene Kazue Miura, Maria Tereza Galvão Guiotti, Rafaella Karen Sousa Monterlei, Adriana Maria Alves de Tommaso, Gabriel Hessel, Maria Ângela Bellomo‐Brandão, Roberta Vacari de Alcantara, Maria Julia Rodrigues Teixeira de Araujo, Daniela Góis Meneses, Regina Sawamura, Cibele Dantas Ferreira Marques, Lucas Rocha Alvarenga, Marise Helena Cardoso Tofoli, Ana Cristina Vieira de Melo, Jussara Melo de Cerqueira Maia, Leticia Helena Caldas Lopes, Eleonora Druve Tavares Fagundes   +23 more
wiley   +1 more source

The rate and predictors of recompensation in patients with decompensated cirrhosis due to metabolic dysfunction-associated liver disease (MASLD). [PDF]

Hepatol Commun
Jiménez-Masip A, Broquetas MT, Muñoz-Martinez S, Serra-Matamala I, Rojo D, Sòria A, El Maimouni C, Pagès L, Pons M, Carrión JA, Ginès P, Genescà J, Graupera I, Pericàs JM.   +13 more
europepmc   +1 more source

Feasibility Study of Combined Systemic Therapy and Carbon‐Ion Radiotherapy for Hepatocellular Carcinoma Patients

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Recent advances in systemic therapy, including tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs), have improved outcomes for hepatocellular carcinoma (HCC) and enabled downstaging strategies that allow subsequent local treatments. Carbon‐ion radiotherapy (CIRT) can provide excellent tumor control with minimal
Daijiro Kobayashi, Kei Shibuya, Yuhei Miyasaka, Kenichiro Araki, Yuichi Yamazaki, Ken Shirabe, Tatsuya Ohno   +6 more
wiley   +1 more source

From Cure to Complexity: Post-SVR Liver and Metabolic Trajectories in Diabetic Patients. [PDF]

Liver Int
Asero C, Franzè MS, Maltese T, La Spada A, Lombardo D, Grisanti C, Russo G, Giandalia A, Pitrone C, Filomia R, Caccamo G, Saitta C, Licata A, Pollicino T, Cacciola I.   +14 more
europepmc   +1 more source

Rapid Progressive Liver Atrophy During Immune Checkpoint Inhibitor Hepatitis: Imaging Perspectives Beyond Aminotransferase Elevation

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Severe immune checkpoint inhibitor–associated hepatitis may progress despite only modest aminotransferase elevations, particularly in patients with cirrhosis. Recognition of atypical presentations and integration of clinical, radiologic, and multidisciplinary assessment may improve risk stratification and guide timely management of clinically ...
Chukwuka Elendu, Adetokunbo A. Adesina, Olisa S. Okabekwa, Ebube C. Mbah, Favour K. Mbakwe   +4 more
wiley   +1 more source

Baclofen Misuse in Clinical Practice: A Case Report on Management Strategies

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Baclofen, a GABA_B receptor agonist, is increasingly linked to misuse and severe withdrawal symptoms, including acute neuropsychiatric manifestations. We present a 26‐year‐old male exhibiting severe substance use disorder and recurrent depressive episodes, accompanied by profound insomnia, suicidal ideation, and visual hallucinations.
Mostafa Yousef, Mohamed Elsayed, Ahmed Hosney Nada, Olivier Uwishema   +3 more
wiley   +1 more source