Results 71 to 80 of about 233,828 (325)

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang   +15 more
wiley   +1 more source

Chemically Driven Nano‐Elastic Heterogeneities Control Fragility in Volcanic Melts

open access: yesAdvanced Science, EarlyView.
The study elucidates how nanoscale structural heterogeneity governs the mechanical behavior of volcanic glasses across compositions from basalt to rhyolite. Using a physicochemical framework, correlation length (ξ) and microscopic free volume (Vc) are derived from vibrational and physical properties, revealing systematic trends with silica content that
Michele Cassetta   +13 more
wiley   +1 more source

Decompression of a giant cranial pseudomeningocele causing haemiparesis and focal seizures [PDF]

open access: bronze, 2022
Kapil Rajwani   +3 more
openalex   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

open access: yesAdvanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin   +19 more
wiley   +1 more source

Ultrasonic Detection of the Intravascular Free Gas Phase in Research on Diving

open access: yesPolish Maritime Research, 2020
The article presents a unique atypical application of the sonography technique and a methodological description of the introduction of this technique to research.
Kłos Ryszard
doaj   +1 more source

Peroneal nerve decompression [PDF]

open access: yesNeurosurgical Focus, 2018
Peroneal neuropathy is a common pathology encountered by neurosurgeons. Symptoms include pain, numbness, and foot drop. When secondary to compression of the nerve at the fibular head, peroneal (fibular) nerve release is a low-risk procedure that can provide excellent results with pain relief and return of function.
Mark, Corriveau   +2 more
openaire   +2 more sources

Reaching the hydrodynamic regime in a Bose-Einstein condensate by suppression of avalanche

open access: yes, 2006
We report the realization of a Bose-Einstein condensate (BEC) in the hydrodynamic regime. The hydrodynamic regime is reached by evaporative cooling at a relative low density suppressing the effect of avalanches.
J. M. Vogels   +4 more
core   +1 more source

Piezofluorochromism in Aramid Dyads: Pressure‐Triggered Luminescence Enhancement with Predictable Emission Shifts

open access: yesAdvanced Science, EarlyView.
High‐pressure investigations uncover the structural determinants of luminescence intensity and shifts in aramids, establishing intrinsic intramolecular rotation as a reliable predictor of their piezofluorochromic behavior. Leveraging this insight, conjugation modulation is proposed as a precise strategy to tune their piezofluorochromic properties ...
Yayun Wang   +10 more
wiley   +1 more source

TRAUMATIC CERVICAL SPINAL CORD INJURY. IS URGENT INTERVENTION SUPERIOR TO DELAYED INTERVENTION? A META-ANALYSIS EVALUATION

open access: yesJournal Orthopaedi and Traumatology Surabaya, 2019
Introduction: Cervical spine is the most mobile part of the human spine, thus making it the most vulnerable compared to all the other vertebral structures.
I Ketut Martiana   +2 more
doaj   +1 more source

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