Results 61 to 70 of about 155,579 (310)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulation
Opto-Electronic ScienceDeconvolution is a commonly employed technique for enhancing image quality in optical imaging methods. Unfortunately, its application in optical coherence tomography (OCT) is often hindered by sensitivity to noise, which leads to additive ringing ...
Xin Ge +6 more
doaj +1 more source
Application of the nanoindentation technique for the characterization of varved clay
Open Geosciences, 2018 Nanoindentation is a test carried out in a small scale, during which a rigid indenter (of known hardness and geometry) is pressed into the tested material.
Tankiewicz Matylda
doaj +1 more source
Nucleic Acids ResearchSingle-cell RNA sequencing (scRNA-Seq) is a recent technology that allows for the measurement of the expression of all genes in each individual cell contained in a sample. Information at the single-cell level has been shown to be extremely useful in many
Hung Nguyen +4 more
semanticscholar +1 more source
Colour deconvolution: stain unmixing in histological imaging
Bioinform., 2020 MOTIVATION Microscopy images of stained cells and tissues play a central role in most biomedical experiments and routine histopathology. Storing colour histological images digitally opens the possibility to process numerically colour distribution and ...
G. Landini +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Determination of EPID convolution kernels for portal imaging using carbon target bremsstrahlung
Current Directions in Biomedical Engineering, 2017 Improving the accuracy and reproducibility during patient positioning is of paramount importance. Hence, the goal of this work is to characterize the aspects of image blurring occurring during carbon target bremsstrahlung portal imaging and to assess the
Lüdeke Sascha +5 more
doaj +1 more source
MuSiC2: cell type deconvolution for multi-condition bulk RNA-seq data
bioRxiv, 2022 Cell type composition of intact bulk tissues can vary across samples. Deciphering cell type composition and its changes during disease progression is an important step towards understanding disease pathogenesis.
Jiaxin Fan +5 more
semanticscholar +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source