Results 51 to 60 of about 143,672 (309)
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Determination of EPID convolution kernels for portal imaging using carbon target bremsstrahlung
Current Directions in Biomedical Engineering, 2017 Improving the accuracy and reproducibility during patient positioning is of paramount importance. Hence, the goal of this work is to characterize the aspects of image blurring occurring during carbon target bremsstrahlung portal imaging and to assess the
Lüdeke Sascha +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
PhotonicsInterferometric scattering microscopy (iSCAT) is widely used for label-free tracking of nanoparticles and single molecules. However, its ability to identify small molecules is limited by low imaging contrast blurred with noise.
Xiang Zhang, Hao He
doaj +1 more source
A Review of Time Relaxation Methods
Fluids, 2017 The time relaxation model has proven to be effective in regularization of Navier–Stokes Equations. This article reviews several published works discussing the development and implementations of time relaxation and time relaxation models (TRMs), and how ...
Sean Breckling, Monika Neda, Tahj Hill
doaj +1 more source
Regression‐assisted deconvolution [PDF]
Statistics in Medicine, 2011 AbstractWe present a semi‐parametric deconvolution estimator for the density function of a random variable biX that is measured with error, a common challenge in many epidemiological studies. Traditional deconvolution estimators rely only on assumptions about the distribution of X and the error in its measurement, and ignore information available in ...
Julie, McIntyre, Leonard A, Stefanski
openaire +2 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Tutorial for the deconvolution of hydrophone measurement data
, 2020 This tutorial presents and explains examples of the deconvolution of hydrophone measurement data. The motivation for performing deconvolution is that, in many cases, measurements of ultrasonic signals are performed with a hydrophone that is (more or less)
Martin Weber +2 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cell Reports MedicineSummary: The tumor microenvironment (TME) contributes to breast cancer heterogeneity and outcome but is rarely considered in clinical decision-making. We address this gap by systematically characterizing the TME’s cellular composition to establish its ...
Kevin J. Tu +10 more
doaj +1 more source