Results 51 to 60 of about 99,307 (266)

Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulation

open access: yesOpto-Electronic Science
Deconvolution is a commonly employed technique for enhancing image quality in optical imaging methods. Unfortunately, its application in optical coherence tomography (OCT) is often hindered by sensitivity to noise, which leads to additive ringing ...
Xin Ge   +6 more
doaj   +1 more source

Application of the nanoindentation technique for the characterization of varved clay

open access: yesOpen Geosciences, 2018
Nanoindentation is a test carried out in a small scale, during which a rigid indenter (of known hardness and geometry) is pressed into the tested material.
Tankiewicz Matylda
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Determination of EPID convolution kernels for portal imaging using carbon target bremsstrahlung

open access: yesCurrent Directions in Biomedical Engineering, 2017
Improving the accuracy and reproducibility during patient positioning is of paramount importance. Hence, the goal of this work is to characterize the aspects of image blurring occurring during carbon target bremsstrahlung portal imaging and to assess the
Lüdeke Sascha   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Contrast-Enhancing Spatial–Frequency Deconvolution-Aided Interferometric Scattering Microscopy (iSCAT)

open access: yesPhotonics
Interferometric scattering microscopy (iSCAT) is widely used for label-free tracking of nanoparticles and single molecules. However, its ability to identify small molecules is limited by low imaging contrast blurred with noise.
Xiang Zhang, Hao He
doaj   +1 more source

A Review of Time Relaxation Methods

open access: yesFluids, 2017
The time relaxation model has proven to be effective in regularization of Navier–Stokes Equations. This article reviews several published works discussing the development and implementations of time relaxation and time relaxation models (TRMs), and how ...
Sean Breckling, Monika Neda, Tahj Hill
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The tumor microenvironment of 14,837 breast cancers is associated with clinical outcome independently of genomic subtypes

open access: yesCell Reports Medicine
Summary: The tumor microenvironment (TME) contributes to breast cancer heterogeneity and outcome but is rarely considered in clinical decision-making. We address this gap by systematically characterizing the TME’s cellular composition to establish its ...
Kevin J. Tu   +10 more
doaj   +1 more source

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