Results 51 to 60 of about 189,551 (288)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Archaeologia Historica, 2015 Stáročný vývoj, ktorým Kostol sv. Margity Antiochijskej v Kopčanoch prešiel, sa zapísal do jeho podoby skladbou interiérových omietkových úprav, výmalieb, výzdob, architektonických článkov a pod., tvoriacich jeho neodmysliteľnú hodnotovú bázu, ktorá ...
Andrej Botek +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Study, typology and classification of carving decorations in the Atiq Mosque of Isfahan With emphasis on the works of Safavid and Qajar periods. [PDF]
نگره, 2019 The use of carving technique is one of the most commonly used architectural decorations in the Islamic buildings that the large number of samples being displayed in the mosques of Isfahan.
farid ahmadzadeh +3 more
doaj +1 more source
Computing Algebraic Matroids [PDF]
, 2014 An affine variety induces the structure of an algebraic matroid on the set of coordinates of the ambient space. The matroid has two natural decorations: a circuit polynomial attached to each circuit, and the degree of the projection map to each base ...
Rosen, Zvi
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Comparative Study on the Stucco Decorations of Two Monuments from the Greater Khorasan: Robat Sharaf and Faryoumad Mosque (Seljuq, Khwarazmian, Ilkhanid) [PDF]
نگره, 2019 Khorasan’s architecture is famous for simple forms in the early Islamic period of Iran. In fact, from the 4th century AH decorations and Stucco decorations flourished; after simplicity of the Khorasan’s school, came an important decoration part in ...
Atefeh Shekofteh
doaj +1 more source
Formal verification in Coq of program properties involving the global state effect [PDF]
, 2013 The syntax of an imperative language does not mention explicitly the state, while its denotational semantics has to mention it. In this paper we present a framework for the verification in Coq of properties of programs manipulating the global state ...
Dumas, Jean-Guillaume +3 more
core +5 more sources
Rules for Computing Symmetry, Density and Stoichiometry in a Quasi-Unit-Cell Model of Quasicrystals
, 2002 The quasi-unit cell picture describes the atomic structure of quasicrystals in terms of a single, repeating cluster which overlaps neighbors according to specific overlap rules.
A. P. Tsai +23 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source