Results 81 to 90 of about 1,264,100 (295)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Young classes of permutations [PDF]

open access: yes, 2012
We characterise those classes of permutations having the property that for every tableau shape either every permutation of that shape or no permutation of that shape belongs to the class.
Albert, Michael
core  

Size-Change Termination as a Contract

open access: yes, 2019
Termination is an important but undecidable program property, which has led to a large body of work on static methods for conservatively predicting or enforcing termination.
Gilray, Thomas   +3 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Screening of acid-decreasing yeasts in fruit fermentation broth and its acid degradation ability [PDF]

open access: yesZhongguo niangzao
Acid-decreasing yeast can lower organic acids in fruit wine, improving its flavor and complexity. Using lemons, oranges, and grapes as raw materials, yeast strains with acid-decreasing capabilities were isolated and screened from the natural fermentation
PENG Xingli, SI Shengli, YANG Kunfan, YANG Qin, LI Xiangyang, ZHOU Min, ZHANG Yulong, YANG Zhirui
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Zero Number Diminishing Property under General Boundary Conditions

open access: yes, 2019
The so-called {\it zero number diminishing property} (or {\it zero number argument}) is a powerful tool in qualitative studies of one dimensional parabolic equations, which says that, under the zero- or non-zero-Dirichlet boundary conditions, the number ...
Lou, Bendong
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Arankings of Trees

open access: yesDiscussiones Mathematicae Graph Theory, 2019
For a graph G = (V, E), a function f : V (G) → {1, 2, . . ., k} is a kranking for G if f(u) = f(v) implies that every u − v path contains a vertex w such that f(w) > f(u).
Pillone D.
doaj   +1 more source

Effects of low tangential permeability in the superficial layer on the frictional property of articular cartilage

open access: yesBiosurface and Biotribology, 2015
The biphasic characteristics of articular cartilage are known to play important roles in cartilage lubrication. However, it is still difficult to biotribologically explain the extremely low friction coefficient observed in articular cartilage.
H. Fujie, K. Imade
doaj   +1 more source

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