Results 91 to 100 of about 741,460 (300)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Linear programming solutions and distance functions under a constant returns to scale technology [PDF]

open access: yes
This note generalizes analytical relationships among activity variables of DEA models previously derived by Boussemart, Briec and Leleu (2007). We relax the asumption of constant returns to scale by showing that the key results hold under a weaker ...
Walter Briec   +2 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Control Technology of Iron Scale of 9.5mm Hot-Rolled Strip Steel SPHC and Application

open access: yesTeshugang, 2017
Production practice at steel works shows that the surface quality of hot-rolled strip with thickness less than 9mm is better but the surface iron scale of hot-rolled strip with thickness more than 9mm is thick easily to come off during uncoiling process ...
殷胜, 卞皓
doaj  

SPATIAL VARIATIONS IN TECHNICAL EFFICIENCY AND RETURN TO SCALE IN THE INDONESIAN ECONOMY [PDF]

open access: yes, 2016
This paper reports an analysis of technical efficiency and returns to scale in the Indonesia economy during 1983-2013 with special attention to the spatial dimension of the economy.
Muchdie, Muchdie
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

The Deviation Issue and Total Completion Time on a Single Machine Scale Subject to Decreasing and Growing Linear Deterioration are Theoretically Addressed

open access: yesWasit Journal for Pure Sciences
We addressed in this research the schedule of activities that are subject to the condition of linear degradation in declining and growing rate states, respectively, with the goal of guaranteeing that the primary process's duration would be fixed (ρ) and
Mohammed Alsudani, Hanan Ali Chachan
doaj   +1 more source

The efficacy of traditional Thai massage in decreasing spasticity in elderly stroke patients

open access: yes, 2014
Thanitta Thanakiatpinyo,1 Supakij Suwannatrai,2 Ueamphon Suwannatrai,2 Phanitanong Khumkaew,2 Dokmai Wiwattamongkol,2 Manmas Vannabhum,2 Somluck Pianmanakit,1 Vilai Kuptniratsaikul1 1Department of Rehabilitation Medicine, 2Center of Applied Thai ...
Thanakiatpinyo T   +7 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Alignment of the Measurement Scale Mark during Immersion Hydrometer Calibration Using an Image Processing System

open access: yesSensors, 2013
The present work presents an improved method to align the measurement scale mark in an immersion hydrometer calibration system of CENAM, the National Metrology Institute (NMI) of Mexico, The proposed method uses a vision system to align the scale mark of
Jose Emilio Vargas-Soto   +7 more
doaj   +1 more source

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