Results 51 to 60 of about 741,460 (300)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Evaluation of the Scale Effect in Agriculture of the Amur Region [PDF]
The relationship between size of farms and their productivity creates continuing debates in the economic literature, devoted to problems of development.
Olga Gennadyevna Vasilyeva +1 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The present contribution is concerned with the modeling and computation of size effects in metallic glasses. For the underlying model description, we resort to a thermodynamically consistent, gradient-extended continuum mechanics approach.
Klusemann Benjamin, Bargmann Swantje
doaj +1 more source
With the rapid change of the social environment, Mainland China has become a new economic market due to the great domestic demand caused by its enormous population and the increasing economic growth rate.
Ridong Hu, Chich-Jen Shieh
doaj +1 more source
Aim: This study aims to determine the effectiveness of home-based pelvic floor muscle training on decreasing the symptoms of stress urinary incontinence and improving the quality of life among multiparous women Methods: Women who were diagnosed with ...
Anandh Srinivasan, Payal Sanghavi
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Deforestation reduces rainfall and agricultural revenues in the Brazilian Amazon
Deforestation in the Amazon region has suggested to influence precipitation in a non-linear way. Here, the authors show that forest loss is associated with decreasing precipitation after a scale-dependent threshold is crossed, which can cause stress on ...
Argemiro Teixeira Leite-Filho +4 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
In the nonparametric data envelopment analysis literature, scale elasticity is evaluated in two alternative ways: using either the technical efficiency model or the cost efficiency model.
Alireza Amirteimoori +2 more
doaj +1 more source

