Results 61 to 70 of about 727 (261)

Quantitative features of memorial urbanonyms in the Kaliningrad region

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки
Based on the analysis of semantic parameters that can be quantified, this article examines the system of memorial urbanonyms in the Kaliningrad region, which developed as a result of the large-scale renaming in the aftermath of World War II, and compares
O. V. Peteshova
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

«Exemplares novelas» e «novelas exemplares»: Os paratextos da ficção em prosa no século XVII [PDF]

open access: yesVia Spiritus, 2012
Selecting as corpus a group of fictional prose narratives of considerable length, published in the 17th century, this paper, entitled ‘«Exemplary novels» and exemplary novels: the paratexts of fiction during the 17th century’ aims to study the group of ...
Maria Inês Nemésio
doaj  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Un mare poet al limbii române [PDF]

open access: yesRevista de Istorie și Teorie Literară, 2007
With the occasion of Fănuş Neagu’s 75th anniversary, Ion Brad, a writer, ambassador and theatre director, collected all the dedications received from his friend on his books during many years.
Ion Brad
doaj  

Autorskie autografy na egzemplarzach starych druków XVI-XVIII w., zachowanych we Lwowskiej Narodowej Naukowej Bibliotece Ukrainy im. Wasyla Stefanyka

open access: yesZ Badań nad Książką i Księgozbiorami Historycznymi, 2018
The author’s autographs in the early printed books from the collection of the Vasyl Stefanyk Lviv National Scientific Library of Ukraine can be grouped in two categories.
Iryna Kachur
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Les divinités honorées par les Thraces en Occident (Ier – IIIe s.) : entre intégration locale et globale

open access: yesMythos
Considering that cultic practices are revealing of the integration of individuals within the local and global scales in which they are living, we propose to investigate a case study: the acts of devotion performed by Thracians settled in the Germanic and
Tiffany Bellon
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

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