Results 51 to 60 of about 5,858 (295)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Nouvelles dédicaces d’Alésia à Apollon Moritasgus
Three new dedications to Apollo Moritasgus are published here which belong to the god’s sanctuary on the eastern edge of Alesia. The first one comes from Espérandieu’s old excavations, in 1910.
Olivier de Cazanove +1 more
doaj +1 more source
19th-century printed dedications as a form of book recommendation
A printed dedication is usually addressed to a particular person. However, since it is included in every copy of the book, it reaches all readers. Its content, often expanded in the 19th century, provided a wealth of interesting information about the ...
Gruca, Anna, Anna Gruca
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Acknowledgements and Dedications
This collection of essays represent a wide range of perspectives on the work being done in digital classics. It honors the life of Allen Ross Scaife, who was instrumental in advancing digital scholarship in the field of classics.
Gregory R. Crane +2 more
openaire +2 more sources
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Vincenza Armani was one of the first actresses in the Commedia dell’Arte of whom we have some news. Endowed with excellent oratory and musical skills, her legacy can be traced in the reports of Mantuan shows of the late Sixties of the Sixteenth century ...
Eloisa Pierucci
doaj +1 more source
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source

