Results 181 to 190 of about 35,686 (231)

Dedifferentiated liposarcoma with chondroblastic osteosarcomatous dedifferentiation

Pathology International, 2000
We describe a rare case of dedifferentiated liposarcoma with features resembling chondroblastic osteosarcoma in the dedifferentiated component. The tumor was removed from the left thigh in a 78‐year‐old male. It consisted of a well‐differentiated liposarcoma and an anaplastic component that contained numerous osteoid and cartilaginous tissues ...
T, Yamamoto, T, Matsushita, T, Marui, K, Mizuno, R, Minami, Y, Hayashi, K, Hanioka   +6 more
exaly   +3 more sources

Primary Orbital Dedifferentiated Liposarcoma

World Neurosurgery, 2020
Primary dedifferentiated liposarcoma of the orbit is a rare condition.A 41-year-old man presented with a history of right ophthalmalgia with eye movement and exophthalmos that had developed 2 months earlier. Neuroimages revealed a right orbital mass located above the superior rectus muscle.
Tetsuyoshi Horiuchi, Daisuke Yamazaki
exaly   +3 more sources

A dedifferentiated liposarcoma of the anterior mediastinum

International Journal of Clinical Oncology, 2009
Dedifferentiated liposarcoma was first described in 1979, and its definition has been recently extended. We found an undiagnosed anterior mediastinal mass in a 56- year-old man for whom we performed a complete tumor resection through median sternotomy.
Ryuta Fukai, Yuki Fukumura
exaly   +3 more sources

Biology and Management of Dedifferentiated Liposarcoma: State of the Art and Perspectives

Journal of Clinical Medicine, 2021
Dedifferentiated liposarcoma (DDL) is defined as the transition from well-differentiated liposarcoma (WDL)/atypical lipomatous tumor (ALT) to non-lipogenic sarcoma, which arises mostly in the retroperitoneum and deep soft tissue of proximal extremities ...
Takuaki Yamamoto, Shizuhide Nakayama
exaly   +2 more sources

Retroperitoneal Dedifferentiated Liposarcoma

American Journal of Clinical Pathology, 2021
Abstract Objectives We aimed to test the hypothesis that in retroperitoneal dedifferentiated liposarcoma (DDLS) the presence of the dedifferentiated (DD) component at the resection margin is associated with adverse outcome. Methods We
Carina A Dehner, Ian S Hagemann, John S A Chrisinger   +2 more
openaire   +2 more sources

Overview of systemic therapy options in liposarcoma, with a focus on the activity of selinexor, a selective inhibitor of nuclear export in dedifferentiated liposarcoma

Therapeutic Advances in Medical Oncology, 2022
Liposarcoma (LPS) is a common soft tissue sarcoma that encompasses diverse subtypes of well-differentiated/dedifferentiated, myxoid/round cell, and pleomorphic LPS.
Neeta Somaiah, Prapassorn Thirasastr
exaly   +2 more sources

Does “Low-Grade” Dedifferentiated Liposarcoma Exist? The Role of Mitotic Index in Separating Dedifferentiated Liposarcoma From Cellular Well-differentiated Liposarcoma

American Journal of Surgical Pathology, 2023
Background: Subjective, varying criteria identify “low-grade” dedifferentiation in well-differentiated/dedifferentiated liposarcoma (WD/DDLPS). The value of mitotic rate (MR) in defining DDLPS is not confirmed.
D. Graham, A. Qorbani, Mark A Eckardt, Kyle D. Klingbeil, Lucia Chen, S. Chopra, F. Eilber, S. Dry   +7 more
semanticscholar   +1 more source

SAR-096: Phase II clinical trial of ribociclib in combination with everolimus in advanced dedifferentiated liposarcoma (DDL), and leiomyosarcoma (LMS).

Clinical Cancer Research, 2023
PURPOSE DDL and LMS are two common subtypes of soft tissue sarcoma, a rare group of diseases for which new treatments are needed. Chemotherapy remains the standard option for advanced disease.
S. Movva, S. Matloob, E. Handorf, E. Choy, P. Merriam, D. Flieder, Kathy Q. Cai, Yan Zhou, Eric D. Tetzlaff, Cheyenne Pagan, Emma Barker, R. Veggeberg, Delia Zumpano, L. Rink, M. von Mehren, S. George   +15 more
semanticscholar   +1 more source

Dedifferentiated liposarcoma of retroperitoneum: spectrum of imaging findings in 15 patients

Clinical Imaging, 2010
BACKGROUND: Dedifferentiated liposarcoma is a high-grade nonlipogenic sarcoma that arises in the background of a preexisting well-differentiated liposarcoma. The purpose of this work is to evaluate the spectrum of radiologic appearance of retroperitoneal
Joon Koo Han, Myeong-Jin Kim, Sun Hwa Hong   +2 more
exaly   +2 more sources

Dedifferentiated Liposarcoma

Advances in Anatomic Pathology, 2016
Well-differentiated liposarcoma (WDL) and dedifferentiated liposarcoma (DDL) form the largest subgroup of liposarcomas, and represent a morphologic and behavioral spectrum of 1 disease entity, which arises typically in middle to late adult life, most frequently within the retroperitoneum or extremities.
Khin, Thway, Robin L, Jones, Jonathan, Noujaim, Shane, Zaidi, Aisha B, Miah, Cyril, Fisher   +5 more
  +5 more sources