Results 201 to 210 of about 297,000 (310)

Deep-sea microbially influenced corrosion and biomineralization. [PDF]

Front Microbiol
Ge Y, Wang C, Etim IN, Khan S, Li C, Yang L, Liu J, Yi P, Liu J, Sand W, Zhang R.   +10 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Sequencing Ultraconserved Elements (UCEs) for Marine Population Genomics: A Proof-of-Concept Using a Deep-Sea Mussel Species. [PDF]

Evol Appl
Li YX, Xu T, Perez M, Chen C, Watanabe HK, Ip JC, Qiu JW.   +6 more
europepmc   +1 more source

Deep Sea Drilling Project [PDF]

Science, 1969
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Deep-sea mining discharge can disrupt midwater food webs. [PDF]

Nat Commun
Dowd MH, Assad VE, Cazares-Nuesser AE, Drazen JC, Goetze E, White AE, Popp BN.   +6 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Method for the Intelligent Identification of the Operating Conditions of Deep-Sea Submersibles and Its Application. [PDF]

Sensors (Basel)
Zhang Y, Li Z, Tang J, He K.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Omics exploration of deep-sea biodiversity: data from the "Pourquoi Pas les Abysses?" and eDNAbyss projects. [PDF]

Sci Data
Arnaud-Haond S, Trouche B, Liautard-Haag C, Alain K, Aubé J, Bonhomme F, Brandt MI, Caillarec-Joly A, Cambon MA, Cornette F, Cueff-Gauchard V, Durand P, de Vargas C, Felix C, Fuchs S, Genoscope Technical Team, Günther B, Henry N, Hourdez S, Jollivet D, Le Port AS, Lesongeur F, Maignien L, Comtet-Marre S, Matabos M, Omnes E, Peyret P, Pradillon F, Sarrazin J, Schauberger C, Tran Lu Y A, Ulloa O, Vaz S, Zeppili D, Viard F, Gavory F, Gaz S, Guy J, Jacoby E, Oliveira PH, Samson G, Aury JM, Wincker P, Pesant S, Poulain J, Belser C.   +45 more
europepmc   +1 more source