Results 141 to 150 of about 8,399 (256)

Livestock Multi‐Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation

Advanced Science, EarlyView.
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen, Zhongyu Wang, Jieping Huang, Fen Li, Ningbo Chen, Yun Ma   +5 more
wiley   +1 more source

Deep-sea mining and its risks for social-ecological systems: Insights from simulation-based analyses. [PDF]

PLoS One
Alam L, Pradhoshini KP, Flint RA, Sumaila UR.   +3 more
europepmc   +1 more source

A strategy for the conservation of biodiversity on mid-ocean ridges from deep-sea mining. [PDF]

Sci Adv, 2018
Dunn DC, Van Dover CL, Etter RJ, Smith CR, Levin LA, Morato T, Colaço A, Dale AC, Gebruk AV, Gjerde KM, Halpin PN, Howell KL, Johnson D, Perez JAA, Ribeiro MC, Stuckas H, Weaver P, SEMPIA Workshop Participants.   +17 more
europepmc   +1 more source

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

Advanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen, Yuqi Zhang, Xinyue Ma, Jinpeng Bi, Fei He, Li Zhao, Haiyue Lei, Zhengqin Xiao, Xue Wang, Tiejun Zhang, Ruicai Long, Junmei Kang, Qingchuan Yang   +12 more
wiley   +1 more source

Probabilistic ecological risk assessment for deep-sea mining: A Bayesian network for Chatham Rise, Pacific Ocean. [PDF]

Ecol Appl
Kaikkonen L, Clark MR, Leduc D, Nodder SD, Rowden AA, Bowden DA, Beaumont J, Cummings V.   +7 more
europepmc   +1 more source

Geomorphological evidence of large vertebrates interacting with the seafloor at abyssal depths in a region designated for deep-sea mining. [PDF]

R Soc Open Sci, 2018
Marsh L, Huvenne VAI, Jones DOB.
europepmc   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Deep-sea mining rock-fragment dispersal scenarios associated with submesoscale forcings: A case study in the Atlantic. [PDF]

Heliyon
Amorim FN, Caetano M, Bastos L, Iglesias I.   +3 more
europepmc   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

Metal Release from Manganese Nodules in Anoxic Seawater and Implications for Deep-Sea Mining Dewatering Operations. [PDF]

ACS ES T Water
Xiang Y, Steffen JM, Lam PJ, Gartman A, Mizell K, Fitzsimmons JN.   +5 more
europepmc   +1 more source