Results 31 to 40 of about 8,399 (256)

Planning Sustainable Deep Sea Mining

Materials Proceedings, 2021
The increase in world population and the expected global development of the world economy after the COVID-19 pandemic will continue to impose unprecedented pressure on securing the supply of minerals.
Konstantinos I. Vatalis, Spyridon Platias, George Charalampides   +2 more
doaj   +1 more source

The Fluid Mechanics of Deep-Sea Mining

Annual Review of Fluid Mechanics, 2023
Fluid mechanics lies at the heart of many of the physical processes associated with the nascent deep-sea mining industry. The evolution and fate of sediment plumes that would be produced by seabed mining activities, which are central to the assessment of the environmental impact, are entirely determined by transport processes.
Peacock, Thomas, Ouillon, Raphael
openaire   +2 more sources

Visual Localization for Deep-Sea Mining Vehicles During Operation

Journal of Marine Science and Engineering
Deep-sea mining operations demand continuous, drift-free positioning over multi-day missions—a requirement that traditional acoustic dead-reckoning systems struggle to meet due to cumulative error accumulation and frequent DVL bottom-lock loss in ...
Yangrui Cheng, Bingkun Wang, Xiaojun Zhuo, Kai Liu, Yingjie Guan   +4 more
doaj   +1 more source

We may not know much about the deep sea, but do we care about mining it?

People and Nature, 2021
The way we value the environment affects how we treat it. While public awareness of human impacts on the ocean is increasing, industrial activities in the deep sea are accelerating rapidly and out of sight.
Laura Kaikkonen, Ingrid vanPutten
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Norwegian Deep Sea Resource Exploitation Strategic Analysis and Suggestion for China

Haiyang Kaifa yu guanli, 2023
In recent years, the Norwegian government has been vigorously promoting deep-sea mining. Norway's geological research and exploration, technical equipment development, environmental policy making and other aspects have been in the forefront of the world,
Ying YU, Chunjuan WANG, Dahai LIU
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

BIIGLE 2.0 - Browsing and Annotating Large Marine Image Collections

Frontiers in Marine Science, 2017
Combining state-of-the art digital imaging technology with different kinds of marine exploration techniques such as modern autonomous underwater vehicle (AUV), remote operating vehicle (ROV) or other monitoring platforms enables marine imaging on new ...
Daniel Langenkämper, Martin Zurowietz, Timm Schoening, Tim W. Nattkemper   +3 more
doaj   +1 more source

A Global Red List for Hydrothermal Vent Molluscs

Frontiers in Marine Science, 2021
With the accelerating development of direct and indirect anthropogenic threats, including climate change and pollution as well as extractive industries such as deep-sea mining, there is an urgent need for simple but effective solutions to identify ...
Elin A. Thomas, Aoife Molloy, Nova B. Hanson, Monika Böhm, Monika Böhm, Mary Seddon, Julia D. Sigwart, Julia D. Sigwart   +7 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source