Results 41 to 50 of about 4,786,586 (289)

Abundance of small individuals influences the effectiveness of processing techniques for deep-sea nematodes [PDF]

, 2010
Nematodes are the most abundant metazoans of deep-sea benthic communities, but knowledge of their distribution is limited relative to larger organisms.
Nodder, Scott D., S.D. Nodder, Leduc, Daniel, K. Berkenbusch, Pilditch, Conrad A., P.K. Probert, D. Leduc, C.A. Pilditch, Berkenbusch, K., Probert, P. Keith   +9 more
core   +1 more source

Deep-Sea Misconceptions Cause Underestimation of Seabed-Mining Impacts [PDF]

, 2020
Scientific misconceptions are likely leading to miscalculations of the environmental impacts of deep-seabed mining. These result from underestimating mining footprints relative to habitats targeted and poor understanding of the sensitivity, biodiversity,
Morato, Telmo, Washburn, T.W., Washburn, Travis, Drazen, J.C., Drazen, Jeffrey C., Gollner, S., Mestre, NC, Tunnicliffe, V, Gollner, S, Sweetman, A.K., Morato, T., Molodtsova, T.N., Smith, Craig R., Metaxas, A., Washburn, T, Colaço, A, Mestre, Nelia C., Levin, LA, Tunnicliffe, Verena, Molodtsova, TN, Tunnicliffe, V., Gollner, Sabine, Metaxas, A, Amon, DJ, Metaxas, Anna, Sweetman, Andrew K., Colaço, A., Mestre, N.C., Levin, L.A., Morato, T, Sweetman, AK, Molodtsova, Tina N., Smith, CR, Smith, C.R., Levin, Lisa A., Drazen, JC, Amon, Diva J., Amon, D.J., Amon, Diva, Colaço, Ana, Mestre, Nélia   +40 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Nonparametric and Parametric Modeling of Hydrodynamics for a Fully Appended Autonomous Underwater Vehicle

Journal of Marine Science and Engineering
Hydrodynamic models underpin Autonomous Underwater Vehicle (AUV) design, motion control, and performance evaluation. Existing methods face two critical bottlenecks: (1) conventional explicit CFD requires predefined trajectories, which fails to capture ...
Yingjie Guan, Xiaoyang Deng, Yougang Bian, Xuan Zeng, Xiaojun Zhuo, Xu Liu   +5 more
doaj   +1 more source

Norwegian Deep Sea Resource Exploitation Strategic Analysis and Suggestion for China

Haiyang Kaifa yu guanli, 2023
In recent years, the Norwegian government has been vigorously promoting deep-sea mining. Norway's geological research and exploration, technical equipment development, environmental policy making and other aspects have been in the forefront of the world,
Ying YU, Chunjuan WANG, Dahai LIU
doaj  

BIIGLE 2.0 - Browsing and Annotating Large Marine Image Collections

Frontiers in Marine Science, 2017
Combining state-of-the art digital imaging technology with different kinds of marine exploration techniques such as modern autonomous underwater vehicle (AUV), remote operating vehicle (ROV) or other monitoring platforms enables marine imaging on new ...
Daniel Langenkämper, Martin Zurowietz, Timm Schoening, Tim W. Nattkemper   +3 more
doaj   +1 more source

We may not know much about the deep sea, but do we care about mining it?

People and Nature, 2021
The way we value the environment affects how we treat it. While public awareness of human impacts on the ocean is increasing, industrial activities in the deep sea are accelerating rapidly and out of sight.
Laura Kaikkonen, Ingrid vanPutten
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A Global Red List for Hydrothermal Vent Molluscs

Frontiers in Marine Science, 2021
With the accelerating development of direct and indirect anthropogenic threats, including climate change and pollution as well as extractive industries such as deep-sea mining, there is an urgent need for simple but effective solutions to identify ...
Elin A. Thomas, Aoife Molloy, Nova B. Hanson, Monika Böhm, Monika Böhm, Mary Seddon, Julia D. Sigwart, Julia D. Sigwart   +7 more
doaj   +1 more source