Results 101 to 110 of about 324,009 (338)

Deep Brain Stimulation

open access: yesBrain Stimulation, 2015
Deep brain stimulation is used as a substitute for permanent neuroablative procedures (destruction/inactivation of nerve tissue by surgery, injections, lasers, etc.) in the management of disorders associated with movement, notably Parkinson’s disease, essential tremor, and dystonia. The technique involves stereotactic placement of an electrode into the
openaire   +4 more sources

RAB39B Related Parkinsonism in an Italian Family: A Unique Use of Advanced Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Parkinson's disease (PD) is a neurodegenerative disorder that may sometimes be caused by deleterious genetic variants. Among them, RAB39B polymorphisms are known as rare causes of early‐onset PD associated with intellectual disability (Waisman's syndrome).
Caterina Del Regno   +13 more
wiley   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

open access: yesArthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox   +3 more
wiley   +1 more source

Association between Discordance of Disease Activity Indices and Quantitative Sensory Testing Measures of Nociplastic Pain in Patients with Rheumatoid Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective This study investigates the association between discordance in commonly collected clinical indicators of rheumatoid arthritis (RA) disease activity and abnormalities in quantitative sensory testing (QST) observed in individuals with nociplastic pain.
Clarice P. Lin   +10 more
wiley   +1 more source

Nucleus accumbens deep brain stimulation in adult patients suffering from severe and enduring anorexia nervosa (STIMARS): protocol for a pilot study

open access: yesFrontiers in Psychiatry
BackgroundAffecting adolescent and young adults, anorexia nervosa (AN) has the highest death rate of all mental disorders. Effective treatment options are lacking and a significant proportion of patients develop severe and chronic forms of the disease ...
Philibert Duriez   +23 more
doaj   +1 more source

Partial improvement in performance of patients with severe Alzheimer's disease at an early stage of fornix deep brain stimulation

open access: yesNeural Regeneration Research, 2018
Deep brain stimulation is a therapy for Alzheimer's disease (AD) that has previously been used for mainly mild to moderate cases. This study provides the first evidence of early alterations in performance induced by stimulation targeted at the fornix in ...
Zhi-Qi Mao   +10 more
doaj   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

open access: yesAdvanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins   +2 more
wiley   +1 more source

Malignant neuroleptic syndrome following deep brain stimulation surgery: a case report

open access: yesJournal of Medical Case Reports, 2011
Background The neuroleptic malignant syndrome is an uncommon but dangerous complication characterized by hyperthermia, autonomic dysfunction, altered mental state, hemodynamic dysregulation, elevated serum creatine kinase, and rigor.
Stavrinou Lampis C   +4 more
doaj   +1 more source

Deep Brain Stimulation [PDF]

open access: yesScience, 2010
Physiology![Figure][1] CREDIT: NAKANE ET AL., PROC. NATL. ACAD. SCI. U.S.A. 107 , 10.1073/PNAS.1006393107 (2010) Seasonal changes are reflected in the phenotype and physiology of many organisms, for example, changes of color or insulating power in fur or feathers, and also in reproductive activity.
openaire   +2 more sources

Bioinspired Materials, Designs, and Manufacturing Strategies for Advanced Impact‐Resistant Helmets

open access: yesAdvanced Engineering Materials, EarlyView.
This review explores how bioinspired materials, structures, and manufacturing strategies transform helmet design to achieve enhanced impact resistance. Drawing inspiration from nacre, porcupine quills, beetle exoskeletons, and skull architectures, it highlights advances in auxetic lattices, nanocomposites, and functionally graded foams.
Joseph Schlager   +4 more
wiley   +1 more source

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