Results 131 to 140 of about 317,965 (338)

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: effects of variation in stimulation parameters [PDF]

, 2001
Mario Giorgio Rizzone
openalex   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

The Insula and Its Epilepsies [PDF]

, 2019
Insular seizures are great mimickers of seizures originating elsewhere in the brain. The insula is a highly connected brain structure. Seizures may only become clinically evident after ictal activity propagates out of the insula with semiology that ...
Gonzalez-Martinez, Jorge, Isnard, Jean, Jobst, Barbara C., Kahane, Philippe, Lacuey, Nuria, Lado, Fred, Lahtoo, Samden D., Nguyen, Dang K., Wu, Chengyuan   +8 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Stimulation-Induced Artifact Removal of the Local Field Potential Through Hardware Design: Toward the Implantable Closed-Loop Deep Brain Stimulation

IEEE Access
Deep brain stimulation is a standard neurosurgery to treat advanced Parkinson’s disease patients. An innovative technology known as closed-loop deep brain stimulation is under development.
Yi-Hui Wu, Hsiao-Chun Lin, Chi-Wei Huang, Chung-Yu Wu, Ming-Dou Ker   +4 more
doaj   +1 more source

Neurostimulators: Potential for excessive heating of deep brain stimulation electrodes during magnetic resonance imaging [PDF]

, 2001
Ali R. Rezai, Daniel A. Finelli, Paul Rugieri, Jean A. Tkach, J.A. Nyenhuis, Frank G. Shellock   +5 more
openalex   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Smart Nanogels as Enzyme‐Driven Nanomotors for Navigating Viscous Physiological Barriers

Advanced Functional Materials, EarlyView.
Two families of urease‐powered nanomotors (NMs), with and without a p‐(2‐hydroxyethyl methacrylate) (p‐HEMA) shell, have been successfully prepared. Both types exhibit effective motion in highly viscous synovial fluid media at low urea concentrations (25 mM).
David Esporrín‐Ubieto, Noelia Ruiz‐González, Valerio Di Carlo, Daniel Sánchez‐deAlcázar, Florencia Lezcano, Anna Pushkareva Fazullina, Samuel Sánchez   +6 more
wiley   +1 more source

Deep brain stimulation-entrained gamma oscillations in chronic home recordings in Parkinson's disease

Brain Stimulation
Background: In Parkinson's disease, invasive brain recordings show that dopaminergic medication can induce narrowband gamma rhythms in the motor cortex and subthalamic nucleus, which co-fluctuate with dyskinesia scores. Deep brain stimulation can entrain
Maria Olaru, Amelia Hahn, Maria Shcherbakova, Simon Little, Wolf-Julian Neumann, Reza Abbasi-Asl, Philip A. Starr   +6 more
doaj   +1 more source